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Record W4413116042 · doi:10.1021/acs.analchem.5c01988

Determining Bimolecular Rate Constants for Annihilation Reactions of Electrogenerated Ru(bpy)<sub>3</sub><sup>2+</sup> Radical Ions by Means of Electrochemiluminescence Transients at a Conventional Electrode and an Ultramicroelectrode: Toward Single Events

2025· article· en· W4413116042 on OpenAlexafffund
Zhenzhong Cai, Kenneth Chu, Jessica Elizabeth Melissa Winslade, In Lee, E. Lord, Ziying Zhan, Congyang Zhang, Jonathan R. Adsetts, Zhifeng Ding

Bibliographic record

VenueAnalytical Chemistry · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsWestern University
FundersNatural Sciences and Engineering Research Council of CanadaWestern UniversityCanada Foundation for InnovationOntario Innovation Trust
KeywordsChemistryAnnihilationReaction rate constantPhotochemistryKineticsNuclear physics

Abstract

fetched live from OpenAlex

This work presents a thorough analytical procedure for measuring ion-annihilation electrochemiluminescence (ECL) reaction kinetics exemplified with Ru(bpy) 3 2+ . Using a 2 mm diameter platinum electrode and a 25 μm diameter platinum ultramicroelectrode (UME), we captured the rapid kinetic profiles of ECL transients during potential-stepping experiments through the use of advanced time-resolved instrumentation. The associated bimolecular annihilation rate constant, k ann, was modeled using two-dimensional (2D) finite element analysis in COMSOL Multiphysics software. The k ann was estimated to be (9 ± 1) × 10 9 M –1 s –1 by fitting simulated ECL transients to experimental data at frequencies of 0.5 Hz, 5 Hz, and higher frequencies. In fact, our 2D model simulating diffusion, reaction, and decay of electroactive species in the vicinity of both conventional macroelectrodes (2 mm) and UMEs has, for the first time, demonstrated effectiveness in extracting crucial chemical information (e.g., reaction mechanisms, intermediate species) and kinetic information (e.g., rate constants, reaction kinetics, mass transport dynamics) from electrochemiluminescence systems. It was discovered that ECL transients at the 25 μm UME represent single events, whereas those at the 2 mm electrode display ensemble ECL kinetic behavior.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.267
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2025
Admission routes2
Has abstractyes

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