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Record W4413151603 · doi:10.1097/ms9.0000000000003696

Raised a eunuch: a case report of testicular loss without androgen replacement in a pre-pubescent boy

2025· article· en· W4413151603 on OpenAlexaff
James R. Agapoff, Richard J. Wassersug, Thomas W. Johnson

Bibliographic record

VenueAnnals of Medicine and Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicTesticular diseases and treatments
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineAndrogenGeneral surgerySurgeryGynecologyInternal medicineHormone

Abstract

fetched live from OpenAlex

Introduction & Importance: Bilateral testicular torsion with testicular loss is a rare condition in prepubertal youth. This case represents one of the only documented cases of a modern, pre-pubertal youth raised as a eunuch through adolescence. Case Presentation: This is a case of a pre-pubertal boy (Z) who suffered bilateral testicular torsion and gonadal loss who was raised as a eunuch through adolescence. Clinical Discussion: Throughout his adolescence, Z demonstrated no deficits in psychosocial functioning, and displayed no intellectual or learning deficits. Compared to his peers and younger brother, Z was less interested in physical and competitive activities, preferring more supportive, pro-social behaviors, like caring for children. Conclusion: In this case, hormonal deprivation and delayed puberty did not appear to impact neurodevelopmental processes or psychosocial development. This case has potential issues for other areas of healthcare where concerns have arisen around long-term pubertal suppression.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0030.002
Scholarly communication0.0020.002
Open science0.0020.002
Research integrity0.0040.004
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.364
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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