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Record W4413207166 · doi:10.12669/pjms.41.8.11679

Clinical effectiveness of double-layer artificial dermis transplantation repairing hand wounds with limited bone and tendon exposure

2025· article· en· W4413207166 on OpenAlexaboutno aff
Congqiang Rao, Jiamin Chen, Bing Xiong, Hsin‐You Ou

Bibliographic record

VenuePakistan Journal of Medical Sciences · 2025
Typearticle
Languageen
FieldMedicine
TopicOrgan and Tissue Transplantation Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineDermisGranulation tissueWound healingSurgeryTransplantationTendonPathology

Abstract

fetched live from OpenAlex

Objective: Our objective was to investigate the clinical efficacy of double-layer artificial dermis transplantation in repairing hand wounds with limited bone and tendon exposure. Methods: This study involved 46 patients with limited bone and tendon exposure in the hand who were admitted to Dongguan Songshan Lake Central Hospital between January 2022 to January 2024. The patients were randomly divided into two groups: observation and control (N=23/group). The observation group underwent double-layer artificial dermis transplantation, whereas the control group received conventional treatment. The two groups were compared in terms of the overall wound condition, infection rate, granulation tissue growth time, wound healing time, pain scores, scar scores, and hand function recovery scores. Results: In the observation group, wound swelling and exudation were significantly reduced post-treatment, while no wound infections were observed. In contrast, the control group had significantly more severe wound swelling and exudation, with an infection rate of 13.04%. The observation group had shorter average times for granulation tissue growth and wound healing. Pain scores at days 3, 7, and 14, Vancouver Scar Scores (VSS) and Arm, Shoulder, and Hand Disability Scores (DASH) at six months were significantly lower in the observation group (P<0.05). Conclusion: The double-layer artificial dermis could effectively reduce the wound's inflammatory response, control infections, alleviate patient pain, accelerate granulation tissue growth and shorten the wound healing time. Furthermore, it could reduce scar tissue formation and restore the hand's functionality.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.057
Threshold uncertainty score0.400

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.432
Teacher spread0.363 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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