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Learning-based autonomous navigation, benchmark environments and simulation framework for endovascular interventions

2025· article· en· W4413257735 on OpenAlexaff
Lennart Karstensen, Harry Robertshaw, Johannes Hatzl, Benjamin M. Jackson, Jens Langejürgen, Katharina Breininger, Christian Uhl, Seyed Mohammad Hadi Sadati, Thomas C. Booth, Christos Bergeles, Franziska Mathis-Ullrich

Bibliographic record

VenueComputers in Biology and Medicine · 2025
Typearticle
Languageen
FieldHealth Professions
TopicHealthcare Operations and Scheduling Optimization
Canadian institutionsArtificial Intelligence in Medicine (Canada)
FundersCentre For Medical Engineering, King’s College LondonEngineering and Physical Sciences Research CouncilKing's College LondonNational Institute for Health and Care Research
KeywordsBenchmark (surveying)Computer sciencePsychological interventionArtificial intelligenceSimulationHuman–computer interactionMedicineGeology

Abstract

fetched live from OpenAlex

Endovascular interventions are a life-saving treatment for many diseases, but they suffer from drawbacks such as radiation exposure and the potential scarcity of proficient physicians. Robotic assistance during these interventions could be a promising support for these problems. Research focusing on autonomous endovascular interventions using artificial intelligence-based methodologies is gaining popularity. However, variability in assessment environments hinders the comparability of different approaches, primarily due to each study employing a unique evaluation framework. In this study, we present autonomous endovascular instrument navigation based on deep reinforcement learning for three distinct digital benchmark interventions: BasicWireNav, ArchVariety, and DualDeviceNav. The benchmarks focus on aortic arch to supra-aortic navigation, representing fundamental large-vessel navigation skills. The benchmark interventions were implemented with our modular simulation framework stEVE (simulated EndoVascular Environment). Autonomous controllers were trained solely in simulation and evaluated in simulation and on physical test benches with camera and fluoroscopy feedback. Autonomous control for BasicWireNav and ArchVariety reached success rates up to 98/100 in simulation and was successfully transferred to the physical test benches with a success rate of up to 97/100. The experiments demonstrate the feasibility of stEVE and its potential to transfer simulation-trained controllers to real-world scenarios. However, they also reveal areas that offer opportunities for future research. Furthermore, this work reduces barriers to entry and increases the comparability of research on learning-based assistance systems for endovascular navigation by providing open-source training scripts, benchmarks, and the stEVE framework. • Novel benchmark environments for autonomous endovascular navigation using stEVE. • Successful simulation-to-reality transfer with 98% to 97% success rate. • Multi-instrument coordination challenges identified in DualDeviceNav benchmark. • Open-source framework enables reproducible endovascular robotics research. • Reward design ablation shows two-component combinations accelerate learning.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.859
Threshold uncertainty score0.360

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.464
Teacher spread0.418 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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