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Record W4413273500 · doi:10.1073/pnas.2422248122

Multisensory feedback makes swimming circuits robust against spinal transection and enables terrestrial crawling in elongate fish

2025· article· en· W4413273500 on OpenAlexaff
Kotaro Yasui, A. K. Gupta, Qiyuan Fu, Shura Suzuki, Jeffrey Hainer, Laura Paez, Keegan Lutek, Jonathan Arreguit, Takeshi Kano, Emily M. Standen, Auke Jan Ijspeert, Akio Ishiguro

Bibliographic record

VenueProceedings of the National Academy of Sciences · 2025
Typearticle
Languageen
FieldEngineering
TopicBiomimetic flight and propulsion mechanisms
Canadian institutionsUniversity of Ottawa
FundersJapan Society for the Promotion of ScienceEuropean Research CouncilMinistry of Education, Culture, Sports, Science and TechnologyHuman Frontier Science Program
KeywordsSpinal cordCrawlingCentral pattern generatorNeuroscienceBiological neural networkElectronic circuitSensory systemTerrestrial locomotionRobustness (evolution)Computer scienceControl theory (sociology)PhysicsAnatomyBiologyArtificial intelligenceAcoustics

Abstract

fetched live from OpenAlex

Vertebrate locomotion is due to the interplay of neural oscillators and sensory feedback loops in the spinal cord that interact with the body and the environment. Here, we study these circuits with a focus on undulatory locomotion as produced by elongated fish such as eels and lampreys. We address three questions: i) How do proprioception (stretch feedback) and exteroception (pressure on skin) interact with local oscillators to generate stable swimming patterns? ii) Can these feedback loops also contribute to dry ground locomotion? iii) Can they explain the remarkable robustness of eels against spinal cord transections? To address these questions, we developed abstract models of the locomotion circuits based on coupled phase oscillators, local stretch and pressure feedback loops, and simulated muscle models that were tested both in simulation and with a real undulatory robot. We also performed swimming experiments with eels before and after spinal cord transections. We found that stretch and pressure feedback work well together in swimming, as they contribute to rapid pattern generation and can, in principle, both replace direct couplings between oscillators. Interestingly, the swimming controllers could generate good ground locomotion when placed in an arena with pegs. For ground locomotion, the stretch feedback is more beneficial than pressure feedback. Finally, our models could replicate the remarkable ability of eels to keep swimming shortly after a full spinal cord transection. We found that stretch feedback and the ability of oscillators to spontaneously oscillate are likely explanations for keeping the neural oscillators active and coordinated below the transection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.063
Threshold uncertainty score0.292

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.262
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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