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Record W4413359130 · doi:10.1109/jbhi.2025.3600652

M$^{2}$SegMamba: Mamba-Based Incomplete Multimodal Learning for Brain Tumor Segmentation With Few Samples

2025· article· en· W4413359130 on OpenAlexaff
Xinyue Zhang, Ali Bahri, Christian Desrosiers, Hui Liu, Fangxun Bao

Bibliographic record

VenueIEEE Journal of Biomedical and Health Informatics · 2025
Typearticle
Languageen
FieldNeuroscience
TopicBrain Tumor Detection and Classification
Canadian institutionsÉcole de Technologie Supérieure
FundersNatural Science Foundation of Shandong ProvinceNational Natural Science Foundation of China
KeywordsComputer scienceArtificial intelligenceSegmentationImage segmentationMedical imagingPattern recognition (psychology)Computer visionNatural language processing

Abstract

fetched live from OpenAlex

The accurate segmentation of brain tumors plays an important role in clinical diagnosis and treatment. Multimodal magnetic resonance imaging (MRI) can provide rich and complementary information for accurate brain tumor segmentation. However, the common problems of incomplete modalities and small samples in clinical practice seriously affect the performance of multimodal segmentation. In this work, we design a new framework, named M$^{2}$SegMamba, using Mamba and Masked Autoencoder networks for both supervised and self-supervised learning, aimed at handling small sample brain tumor segmentation under various incomplete multimodality settings. We construct a masking strategy suitable for multimodal brain tumors to precisely extract image features, which serves as the foundation for image segmentation. By fully leveraging the capabilities of the Mamba network, we design a multi-traversal method to facilitate the interaction between inter-modal and cross-modal image features. Meanwhile, the introduction of TSmamba in skipping connections efficiently integrates multimodal features. Auxiliary regularizers are introduced in both the encoder and decoder to further enhance the model's robustness to incomplete modalities. We conducted experiments on the BraTS 2018 and BraTS 2020 datasets, and the results demonstrate that our method outperforms state-of-the-art brain tumor segmentation methods on most subsets of missing modalities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.869
Threshold uncertainty score0.322

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.342
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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