MétaCan
Menu
Back to cohort
Record W4413379395 · doi:10.5152/pcp.2025.241028

Brief Manual for Multi-Modal Motion-Assisted Memory Desensitization and Reconsolidation Therapy for the Treatment of Post-traumatic Stress Disorder

2025· article· en· W4413379395 on OpenAlexaff
Eric Vermetten, Lisa Burback, Phillip R. Sevigny, Mirjam J. Nijdam, Olga Winkler, Emmanuel P. Espejo, Pinata H. Sessoms, Katherine Bright, Michael J. Roy, Suzette Brémault‐Phillips

Bibliographic record

VenuePsychiatry and Clinical Psychopharmacology · 2025
Typearticle
Languageen
FieldPsychology
TopicCognitive Functions and Memory
Canadian institutionsMount Royal UniversityThompson Rivers UniversityUniversity of CalgaryUniversity of Alberta
Fundersnot available
KeywordsDesensitization (medicine)Memory consolidationModalTraumatic stressEye movement desensitization and reprocessingPsychologyPhysical medicine and rehabilitationPsychotherapistMedicineNeurosciencePosttraumatic stressClinical psychologyInternal medicineMaterials science

Abstract

fetched live from OpenAlex

Multi-Modal Motion-Assisted Memory Desensitization and Reconsolidation (3MDR) is an innovative exposure-based immersive psychotherapeutic intervention for the treatment of post-traumatic conditions such as post-traumatic stress disorder (PTSD) and other related trauma disorders. This manual reviews the theoretical foundations, protocol, and key therapeutic processes of 3MDR, emphasizing its applicability across clinical and research settings. Developed to overcome barriers to traditional trauma-focused psychotherapies, 3MDR combines immersive virtual reality (VR), motion-assisted engagement, and personalized trauma cues to facilitate memory processing and emotional reconsolidation. The 3MDR integrates VR technology, treadmill-assisted movement, and dual-attention tasks to create a dynamic and interactive therapeutic environment. The intervention consists of 3 phases: pre-platform preparation, platform exposure, and post-platform reconsolidation, allowing for structured and progressive trauma processing. Patients engage with self-selected trauma-related images and music, guided by a therapist, to confront distressing memories, reduce avoidance, and foster emotional regulation. The dual-attention task and affect labeling enhance cognitive and emotional integration, while walking promotes a sense of agency and movement through trauma. Clinical research demonstrates 3MDR's efficacy in reducing PTSD symptoms, depression, and anxiety, with high acceptability and low dropout rates among military personnel, veterans, and first responders. Emerging evidence suggests its adaptability for diverse populations, including civilians and individuals with complex trauma histories. This manual provides detailed guidance for implementing 3MDR, underscoring the importance of therapist training, ethical considerations, and continued research to optimize its application and expand access to this promising intervention. This manual should be seen as a companion and not a replacement for training.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.096
Threshold uncertainty score0.321

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0960.023

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.443
Teacher spread0.384 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuePsychiatry and Clinical PsychopharmacologySame topicCognitive Functions and MemoryFrench-language works237,207