Genome-wide identification and expression profiles of the superoxide dismutase (SOD) genes in Lentinula edodes
Bibliographic record
Abstract
The superoxide dismutase (SOD) enzymes are a group of key enzymes involved in oxidative stress defense and play a significant role in organismal growth and development. The SOD gene family has been identified in many plants, animals, and some fungi but not in the economically important edible mushroom Lentinula edodes. In this study, members of the SOD gene family of L. edodes were identified and analyzed using bioinformatic methods. Three proteins containing signature SOD domains were identified in each of the two monokaryotic strains SP3 and SP30 of L. edodes, and all six proteins belonged to the major Fe/Mn-SOD type. Phylogenetic analysis revealed that these LeSOD genes were classified into two subtypes, with members of each type sharing the same conserved motifs. Transcriptome data of mycelia grown under different conditions showed that LeSOD1 was significantly up-regulated under heat stress, while LeSOD2 was significantly up-regulated under hydrogen peroxide stress. Together, the genomic and transcriptomic analyses suggest that LeSOD1 and LeSOD2 are key genes for L. edodes to respond to abiotic stresses. This study provides a foundation for understanding both the roles of the SOD gene family and the molecular mechanism by which L. edodes responds to heat and oxidative stresses.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".