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Record W4413394307 · doi:10.1007/s43678-025-00999-y

Aortic dissection in the ED: a medico-legal perspective on diagnostic delays and failures

2025· article· en· W4413394307 on OpenAlexaff
Jacqueline H. Fortier, Mehrnaz Mostafapour, Robert Ohle, Kate Barbosa, Richard Liu, Ming Hao Guo, Gary Garber, Heather Murray

Bibliographic record

VenueCanadian Journal of Emergency Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicAortic Disease and Treatment Approaches
Canadian institutionsUniversity of OttawaNOSM UniversityQueen's UniversityHealth Sciences NorthCanadian Medical Protective Association
Fundersnot available
KeywordsMedicineAortic dissectionMedical diagnosisEmergency departmentThematic analysisMedical emergencyHarmTriageEmergency medicineGeneral surgeryIntensive care medicineQualitative researchSurgeryAortaRadiologyPsychiatry

Abstract

fetched live from OpenAlex

PURPOSE: Aortic dissection is a life-threatening emergency and delayed or missed diagnoses can result in significant morbidity and mortality for patients. METHODS: We conducted a quantitative and qualitative analysis of medico-legal cases from a national repository involving thoracic aortic dissection seen in the emergency department during a 10-year period. We thematically analyzed peer expert criticism of the care in these cases, including provider, team, and systems factors related to diagnostic issues. We also applied two clinical decision tools to explore whether use of these tools could have affected the diagnostic process. RESULTS: Of 3,531 medico-legal cases in the emergency department during our study period, just 43 were related to aortic dissection. Patients were primarily male (68.2%), presented for care at large urban centers (65.1%), and were triaged as urgent or emergent (72.1%). Thirty-six patients died of their aortic dissection. A thematic analysis identified atypical presentations, diagnostic anchoring, misinterpretation or misuse of tests, communication breakdowns, and resource limitations as common in these cases. CONCLUSIONS: Missed diagnoses of aortic dissection in the ED often result from a combination of cognitive, communication, and system-level factors. Understanding these contributors can inform evidence-based, systems-level supports and strategies to enhance diagnostic accuracy and reduce patient harm.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.022
metaresearch head score (Gemma)0.086
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.022
Threshold uncertainty score0.118

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0220.086
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0030.003
Science and technology studies0.0060.010
Scholarly communication0.0050.008
Open science0.0010.006
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.343
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Journal of Emergency Medicine→Same topicAortic Disease and Treatment Approaches→French-language works237,207→