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Record W4413427612 · doi:10.1097/jdpa.0000000000000074

Clinical utility of a digital dermoscopy image-based artificial intelligence device in the diagnosis and management of skin cancer by dermatology health care providers, primary care providers, and nondermatology specialized physicians

2025· article· en· W4413427612 on OpenAlexaff
Renata Block, Andrew Baker, Alex Brown, Matthew Brunner, Joshua Burshtein, Anne Lee, Joanna Łudzik, Gina Mangin, Margaret Oliviero, Elizabeth Otter, Giovanni Pellacani, Harold Rabinovitz, Darrell S. Rigel, Alexandra Verdieck, John T. Vetto, Cezary Wójcik, Alexander Witkowski

Bibliographic record

VenueJournal of Dermatology for Physician Assistants · 2025
Typearticle
Languageen
FieldMedicine
TopicCutaneous Melanoma Detection and Management
Canadian institutionsBrandon Regional Health Authority
Fundersnot available
KeywordsTeledermatologySkin cancerPrimary careMedicineHealth careDermatologyMedical emergencyCancerFamily medicineTelemedicineInternal medicine

Abstract

fetched live from OpenAlex

Background: Patients with skin lesions suspicious of skin cancer or atypical nevi frequently present to dermatology health care providers (DHPs), primary care providers (PCPs), and nondermatology specialized physicians (NDSPs) who have variable training in the triage and diagnosis of skin cancers and atypical melanocytic nevi. Objective: To evaluate the clinical utility of a digital dermoscopy image-based artificial intelligence algorithm (DDI-AI device) on the diagnosis and management of skin cancers by DHPs, PCPs, and NDSPs. Study Design: Forty-three United States licensed DHPs, PCPs, and NDSPs evaluated 50 clinical images and 50 digital dermoscopy images (DDIs) of the same skin lesions (25 malignant and 25 benign), first without and then with knowledge of the DDI-AI device output. Participants selected whether they thought the lesion was likely benign or malignant. Results: The overall management sensitivity for participants was 94.2% with the DDI-AI device, 84.1% with DDI, and 72.9% with clinical images; overall diagnostic sensitivity for participants was 87.0%, 79.6%, and 64.7%, respectively. Diagnostic specificity increased over baseline to 75.0% with the DDI-AI device, while no significant difference was observed in management specificity. DHPs had a statistically significantly higher baseline clinical (68.5% sensitivity vs. 59.6%) and dermoscopy (84.3% sensitivity vs. 73.3%) performance than PCPs and NDSPs. DHPs also achieved the highest diagnostic performance (87.7% sensitivity vs. 86.2%) when using the DDI-AI device. Conclusions: The use of the DDI-AI device may quickly, safely, and effectively improve skin cancer management and diagnosis when used by DHPs, PCPs, and NDSPs, independent of variable training and clinical experience.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.020
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.020
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.354
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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