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Record W4413437741 · doi:10.33820/mdvi.v52i1.485

KEBERHASILAN TERAPI LUKA BAKAR SUPERFICIAL PARTIAL-THICKNESS DENGAN ASTAXANTHIN SISTEMIK DAN TOPIKAL: SEBUAH LAPORAN KASUS

2025· article· id· W4413437741 on OpenAlexaff
Ninda Sari, Nelly Herfina Dahlan

Bibliographic record

VenueMedia Dermato Venereologica Indonesiana · 2025
Typearticle
Languageid
FieldAgricultural and Biological Sciences
TopicMedicinal Plant Research
Canadian institutionsSKiN Health
Fundersnot available
KeywordsAstaxanthinMedicineDermatologyChemistryFood science

Abstract

fetched live from OpenAlex

ABSTRAK Luka bakar pada kulit terjadi ketika sebagian atau seluruh lapisan kulit rusak akibat energi fisik. Paska terjadi luka bakar, beberapa faktor seperti iskemia, stres oksidatif, peradangan, dan kematian sel (nekrosis atau apoptosis), berkontribusi terhadap konversi luka bakar menjadi lebih luas atau lebih dalam dari lokasi awal. Astaxanthin (ASX) merupakan karotenoid alami yang memiliki efek antioksidan yang kuat dan anti-inflamasi sehingga sangat berperan dalam penyembuhan luka, termasuk luka bakar. Dilaporkan satu kasus luka bakar derajat dua (superficial partial-thickness) akibat terkena air panas pada seorang perempuan berusia 28 tahun dengan tipe kulit Fitzpatrick III. Pengobatan yang diberikan berupa analgetik non steroid, ASX sistemik, formulasi topikal gentamisin dan ASX berbasis krim gel, dan memberikan penyembuhan luka komplit dalam 10 hari, tidak terjadi infeksi dan tanpa gejala sisa skar hipertrofik. Berdasarkan beberapa penelitian menunjukkan bahwa ASX berperan dalam semua fase penyembuhan luka, sehingga dapat digunakan untuk pengobatan luka bakar. Stres oksidatif dan apoptosis sekunder terkait mitokondria memiliki peran penting dalam perkembangan dini luka bakar dan inflamasi yang berkepanjangan. Penyembuhan luka tanpa skar merupakan salah satu tujuan penatalaksanaan luka bakar, sehingga tindakan yang tepat, cepat dan komprehensif sangat penting. Kombinasi ASX sistemik dan topikal memberikan efek penyembuhan yang lebih cepat untuk luka bakar partial-thickness.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.261
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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