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Evaluating SnapshotNIR for Tissue Oxygenation Measurement Across Skin Types After Mastectomy

2025· article· en· W4413440878 on OpenAlexaboutno aff
Saif Badran, Sara Saffari, William R. Moritz, Gary B. Skolnick, Amanda M. Westman, Mitchell A. Pet, Justin M. Sacks

Bibliographic record

VenueBioengineering · 2025
Typearticle
Languageen
FieldMedicine
TopicOptical Imaging and Spectroscopy Techniques
Canadian institutionsnot available
FundersWashington University School of Medicine in St. LouisWashington University in St. Louis
KeywordsOxygenationMastectomyMedicineComputer scienceBiomedical engineeringInternal medicineIntensive care medicineBreast cancerCancer

Abstract

fetched live from OpenAlex

Accurate monitoring of mastectomy skin flap (MSF) perfusion is critical, especially in patients with darker skin pigmentation at higher risk of misdiagnosed tissue ischemia. Near-infrared spectroscopy (NIRS) devices, such as SnapshotNIR, offer real-time tissue oxygen saturation measurements (StO2), but their accuracy across skin pigmentation levels remains unexplored. This quasi-experimental study included 33 patients undergoing mastectomy. MSF edge ΔStO2, defined as preoperative minus postoperative StO2, was measured using SnapshotNIR device (Kent Imaging, Calgary, AB, Canada) pre- and post-mastectomy. By definition, a positive ΔStO2 indicates a decrease in tissue oxygenation, while a negative ΔStO2 indicates an increase relative to baseline. ΔStO2 was analyzed against Fitzpatrick scores to assess skin pigmentation impact on measurement accuracy. ΔStO2 (mean ± SD) progressively decreased with increasing Fitzpatrick score: 14.0 ± 22.98 for score 1, 6.87 ± 17.45 for score 2, −3.13 ± 6.89 for score 3, and −40.75 ± 22.27 for score 5, indicating a shift from positive to negative O2 change. Fitzpatrick scores significantly correlated with ΔStO2 (ρ = −0.392, p = 0.016). ANOVA confirmed differences (p = 0.008), with Tukey’s post hoc testing showing significant differences between Fitzpatrick scores 1 and 5 (p = 0.022), and 2 and 5 (p = 0.006). SnapshotNIR technology demonstrated measurable sensitivity for detecting changes in StO2 and predicting ischemia; however, NIRS-based devices may overestimate oxygenation in darker skin pigmentation, highlighting a need for device calibration to improve accuracy across skin tones.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.401
Teacher spread0.361 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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