MétaCan
Menu
← Back to cohort
Record W4413470660 · doi:10.1080/29973368.2025.2543706

Understanding Bidirectional Relations Between Adolescent Cannabis Use and Internalizing and Externalizing Symptoms: A Longitudinal Study of Canadian Youth

2025· article· en· W4413470660 on OpenAlexafffundabout
Matthew N. Hill, Rebecca Haines‐Saah, Daniel C. Kopala‐Sibley

Bibliographic record

VenueJournal of Child & Adolescent Substance Use · 2025
Typearticle
Languageen
FieldMedicine
TopicCannabis and Cannabinoid Research
Canadian institutionsUniversity of Calgary
FundersCanadian Institutes of Health ResearchBrain and Behavior Research Foundation
KeywordsCannabisPsychologyAdolescent developmentLongitudinal studyDevelopmental psychologyExternalizationLongitudinal dataClinical psychologyPsychiatryMedicineSociologySocial psychologyDemography

Abstract

fetched live from OpenAlex

Cannabis use among adolescents and young adults has become a growing concern due to its potential impact on mental health outcomes. While existing literature has explored the link between cannabis use and adolescent mental health, there remains a gap in understanding the direction of the relationship between cannabis use in teens and externalizing (e.g., conduct problems, aggression, attention problems) and internalizing symptoms (e.g., depression, anxiety) over time. Moreover, there is little knowledge of how adolescent mental health may predict first lifetime use of cannabis. This study examined the association between cannabis use and externalizing and internalizing symptoms in youth over an 18-month period. One hundred twenty-eight cannabis-naïve adolescents at familial high risk for mood and anxiety disorders underwent assessment, with 22 participants reporting first lifetime cannabis use at the 18-month follow-up. Controlling for child sex and age, increased baseline externalizing symptoms and decreased internalizing symptoms predicted first-time cannabis use at follow-up. Cannabis use was linked to an increase in both internalizing and externalizing symptoms over time. No interactive effect of baseline internalizing and externalizing symptoms on cannabis use was observed. Among youth who used cannabis, greater frequency of use was associated with higher externalizing symptoms but not internalizing symptoms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.031
Threshold uncertainty score0.076

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0030.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.110
GPT teacher head0.310
Teacher spread0.200 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

Explore more

Same venueJournal of Child & Adolescent Substance Use→Same topicCannabis and Cannabinoid Research→French-language works237,207→