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Record W4413481149 · doi:10.1101/2025.08.21.25334144

Understanding the Psychological Factors that Impact Hypertension: A Systematic Review

2025· preprint· en· W4413481149 on OpenAlexaboutno aff
Awele Rosemary Ebigwei Omeda, Marcus Chilaka, Masoud Mohammadnezhad, Eleftheria Vaportzis

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldPsychology
TopicHealth and Well-being Studies
Canadian institutionsnot available
FundersNational Institute for Health and Care Research
KeywordsPsychologyClinical psychology

Abstract

fetched live from OpenAlex

Abstract The development and management of hypertension strongly depends on psychological elements which include depression, anxiety together with stress and psychosocial support. This review analysed psychological elements that affect hypertension development from the year 2014 to 2025. The research identified 106 studies through a systematic database search of MEDLINE, Embase, PsycINFO, Scopus and CINAHL. Due to diverse methodologies, the research employed a narrative synthesis approach. The risk of bias was assessed using the Cochrane Risk of Bias Tool, Newcastle–Ottawa Scale, Domain-Based Approach, CASP, and ROB-MR Instrument. Results indicated that both depression and anxiety increased the risk of developing hypertension and decreased adherence to treatment. In contrast, mindfulness-based interventions showed potential blood pressure lowering effects, although evidence for long term outcomes is limited. People with strong psychosocial support networks and higher levels of life satisfaction had better medication adherence and lower stress levels. However, the current evidence base shows that most studies originate from high-income countries, with low- and middle-income countries having limited evidence and most low-income settings contributing only one or two studies, with no more than four studies per country. The results support the need to integrate physical and mental health care models in the management of hypertension. To enhance understanding of the psychological aspects of hypertension, future research should include underrepresented regions and implement both longitudinal and qualitative methods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.038
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.009
Threshold uncertainty score0.042

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.038
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0060.006
Bibliometrics0.0090.010
Science and technology studies0.0010.001
Scholarly communication0.0030.003
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.295
GPT teacher head0.432
Teacher spread0.138 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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