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Record W4413489735 · doi:10.1038/s41598-025-15961-2

Incidence of postoperative cognitive dysfunction in older adults: a prospective cohort study using a web-based Montreal cognitive assessment application

2025· article· en· W4413489735 on OpenAlexaboutno aff
Panithi Pongraweewan, Surapa Tornsatitkul, Arunotai Siriussawakul, Vijay Krishnamoorthy, Nipaporn Sangarunakul, Chalita Jiraphorncharas, Solaphat Hemrungrojn, Natawut Nupairoj

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicIntensive Care Unit Cognitive Disorders
Canadian institutionsnot available
FundersFaculty of Medicine Siriraj Hospital, Mahidol UniversityNational Research Council of ThailandMahidol University
KeywordsMontreal Cognitive AssessmentMedicinePostoperative cognitive dysfunctionProspective cohort studyCognitionIncidence (geometry)CohortCohort studyPopulationCognitive declineRisk factorInternal medicineDementiaDiseaseCognitive impairmentPsychiatry

Abstract

fetched live from OpenAlex

Thailand is transitioning into a super-aged society, and its growing elderly population faces an increased risk of postoperative cognitive dysfunction (POCD). Despite its association with reduced quality of life and heightened mortality, POCD remains underdiagnosed. This study aimed to evaluate the incidence of POCD using a web-based Montreal Cognitive Assessment application (Auto-MoCA) at 1 week postoperatively. We also compared characteristics between patients with and without POCD and examined recovery patterns at 3 months. We conducted a prospective, descriptive cohort study at a university hospital in Bangkok, enrolling Thai-speaking patients aged ≥ 60 years who underwent major elective surgery. Cognitive function was repeatedly assessed via the Auto-MoCA application at baseline, 1 week, and 3 months. POCD was defined as a decrease of ≥ 2 points from baseline. Among 169 enrolled patients, 111 completed the 1-week assessment. POCD occurred in 40.5%, with significant declines in visuospatial, attention, language, abstraction, and orientation domains. Cardiovascular disease was a significant risk factor. By 3 months, 85 patients repeated the Auto-MoCA test. Of these, 34 (40.0%) had developed POCD compared to their baseline results, with 42.9% of affected patients recovered, primarily demonstrating improvements in visuospatial, attention, and delayed recall domains. Postoperative cognitive dysfunction (POCD) was common in older adults, affecting over 40% of patients at both 1 week and 3 months after surgery. With Cardiovascular disease emerged as a significant risk factor. However, nearly half of those affected showed cognitive recovery by 3 months. Underscoring the utility of digital cognitive assessment tools, such as the Auto-MoCA application, and highlight the need for future interventional research aiming to facilitate cognitive recovery in older adults following surgery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.304
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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