Eruptive acral syringomas: A case report and review of literature
Bibliographic record
Abstract
We present a case of a 43-year-old woman with Vogt-Koyanagi-Harada syndrome, on adalimumab, methotrexate, and risedronate, who developed pruritic, skin-colored papules on the dorsal hands. A biopsy revealed features consistent with syringomas. Syringomas are benign eccrine duct tumors that typically appear as small, shiny papules, most often in the periorbital area but can also present in acral regions. Only 14 cases of exclusive acral syringomas have been reported. Eruptive variants may resemble conditions such as lichen nitidus or warts, making dermoscopy and histopathology crucial for diagnosis. Dermoscopically, syringomas may show fine reticulate brown lines and homogenous pigmentation. Histologically, they show small ductal structures and epithelial cords in the dermis. Their exact pathogenesis remains unclear, possibly involving hormonal or inflammatory triggers. Treatment is challenging due to their dermal depth and recurrence risk, with lasers and retinoids among the options. This case highlights the diagnostic complexity of acral eruptive syringomas.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".