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Record W4413611804 · doi:10.1002/acr.25637

Knee Crepitus and Osteoarthritis Features in Young Adults Following Traumatic Knee Injury

2025· article· en· W4413611804 on OpenAlexafffund
J. Couch, Brooke Patterson, Kay M. Crossley, Ali Guermazi, Matthew King, Danilo de Oliveira Silva, Jackie L. Whittaker, M. Girdwood, Adam G Culvenor

Bibliographic record

VenueArthritis Care & Research · 2025
Typearticle
Languageen
FieldMedicine
TopicKnee injuries and reconstruction techniques
Canadian institutionsUniversity of British ColumbiaArthritis Research Centre of CanadaResearch Canada
FundersMedical Research CouncilCentre for Hip Health and MobilityUniversity of MelbourneLa Trobe UniversityNational Health and Medical Research CouncilArthritis AustraliaAustralian Government
KeywordsOsteoarthritisMedicinePhysical therapyKnee painQuality of life (healthcare)RehabilitationSurgery

Abstract

fetched live from OpenAlex

OBJECTIVE: This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self-reported outcomes in young adults following traumatic knee injury. METHODS: One year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years old) self-reported the presence and/or absence of knee crepitus using an item from the Knee Injury and Osteoarthritis Outcome Score (KOOS). Patellofemoral and tibiofemoral osteoarthritis features (ie, cartilage lesions, osteophytes, and bone marrow lesions) were assessed from magnetic resonance imaging scans at one and five years after ACLR. Self-reported outcomes were assessed with two KOOS subscales (pain and quality of life [QoL]) and the International Knee Documentation Committee subjective evaluation form (ie, self-reported function). Poisson regression evaluated the relationship between self-reported crepitus and the presence/worsening of structural osteoarthritis features. General linear models explored the relationship between crepitus and self-reported outcomes. RESULTS: Self-reported crepitus was associated with full-thickness patellofemoral cartilage lesions one year after ACLR (prevalence ratio 2.70, 95% confidence interval [CI] 1.41-6.39) but not the risk of worsening structural osteoarthritis features between one and five years after ACLR. Those with crepitus reported worse pain (β = -6.42, 95% CI -10.47 to -2.36), QoL (β = -10.39, 95% CI -18.58 to -2.20), and function (β = -5.49, 95% CI -10.92 to -0.06) one year after ACLR but greater improvement in pain and function between one and five years. CONCLUSION: Self-reported knee crepitus was associated with the presence of full-thickness patellofemoral cartilage defects one year after ACLR but was not associated with a greater risk of worsening structural osteoarthritis features up to five years after ACLR. One year after ACLR, those with crepitus reported worse pain, knee-related QoL, and function.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.337
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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