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Record W4413682207 · doi:10.1152/ajpendo.00286.2025

Oral glucose tolerance test-induced increases in femoral blood flow are absent in nonobese females with polycystic ovary syndrome

2025· article· en· W4413682207 on OpenAlexafffund
Danielle E. Berbrier, Will Huckins, Emily K Van Berkel, Shannon I. Delage, Sarkis J. Hannaian, Raychel Myara, Tun-Hui Chung, Togas Tulandi, S.L. Reinblatt, Rachel N. Lord, Tyler A. Churchward‐Venne, Charlotte W. Usselman

Bibliographic record

VenueAmerican Journal of Physiology-Endocrinology and Metabolism · 2025
Typearticle
Languageen
FieldMedicine
TopicOvarian function and disorders
Canadian institutionsCollège de MaisonneuveMcGill University Health CentreMcGill University
FundersFonds de Recherche du Québec - SantéNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchFonds de recherche du Québec
KeywordsPolycystic ovaryInternal medicineEndocrinologyMedicineInsulin resistanceInsulinBody mass indexArea under the curveImpaired glucose tolerance

Abstract

fetched live from OpenAlex

To the best of our knowledge, this is the first study to demonstrate that nonobese females with polycystic ovary syndrome (PCOS) do not exhibit oral glucose tolerance test-induced increases in peripheral blood flow, unlike healthy controls. These findings highlight the peripheral vasculature as a critical and overlooked component of cardiometabolic dysfunction in PCOS, even in the absence of obesity and other cardiometabolic risk factors (e.g., hypertension and diabetes).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.129
Threshold uncertainty score0.800

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.255
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueAmerican Journal of Physiology-Endocrinology and MetabolismSame topicOvarian function and disordersFrench-language works237,207