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Record W4413800245 · doi:10.1101/2025.08.26.25333975

How Good Are Large Language Models at Supporting Frontline Healthcare Workers in Low-Resource Settings – A Benchmarking Study & Dataset

2025· preprint· en· W4413800245 on OpenAlexaff
Samuel Rutunda, Gwydion Williams, Kleber Kabanda, Solange Uwiduhaye, Eulade Rugegamanzi, Cyprien Nshimiyimana, Vasihnavi Menon, Mira Emmanuel-Fabula, Xiaoxuan Liu, Emery Hezagira, Bilal A. Mateen

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsPrograms for Assessment of Technology in Health Research Institute
FundersBill and Melinda Gates Foundation
KeywordsRubricBenchmarkingLikert scaleMetric (unit)Health careResource (disambiguation)MedicinePsychologyComputer scienceBusinessMarketingEconomicsEconomic growthDevelopmental psychologyMathematics education

Abstract

fetched live from OpenAlex

Abstract Large language models (LLMs) have demonstrated strong performance in medical contexts; however, existing benchmarks often fail to reflect the real-world complexity of low-resource health systems accurately. This study developed a dataset of 5,609 clinical questions contributed by 101 community health workers (CHWs) across four Rwandan districts and compared responses generated by five large language models (LLMs) (Gemini-2, GPT-4o, o3 mini, Deepseek R1, and Meditron-70B) with those from local clinicians. A subset of 524 question-answer pairs was evaluated using a rubric of 11 expert-rated metrics, scored on a five-point Likert scale. Gemini-2 and GPT-4o were the best performers (achieving mean scores of 4.49 and 4.48 out of 5, respectively, across all 11 metrics). All LLMs significantly outperformed local clinicians (ps < 0.001) across all metrics, with Gemini-2, for example, surpassing local GPs by an average of 0.83 points on every metric (range: 0.38 – 1.10). While performance degraded slightly when LLMs communicated in Kinyarwanda, the LLMs remained superior to clinicians and were over 500 times cheaper per response. These findings support the potential of LLMs to strengthen frontline care quality in low-resource, multilingual health systems.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.030
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.063

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.030
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0020.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.095
GPT teacher head0.415
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2025
Admission routes1
Has abstractyes

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Same venuemedRxivSame topicArtificial Intelligence in Healthcare and EducationFrench-language works237,207