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Record W4413812319 · doi:10.2196/75015

COVID-19 Pneumonia Diagnosis Using Medical Images: Deep Learning–Based Transfer Learning Approach

2025· article· en· W4413812319 on OpenAlex
Anjali Dharmik

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJMIRx Med · 2025
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 diagnosis using AI
Canadian institutionsnot available
Fundersnot available
KeywordsPreprintCoronavirus disease 2019 (COVID-19)Transfer of learningSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia2019-20 coronavirus outbreakDeep learningArtificial intelligenceComputer scienceVirologyMedicineInfectious disease (medical specialty)PathologyWorld Wide WebInternal medicine

Abstract

fetched live from OpenAlex

Background: SARS-CoV-2, the causative agent of COVID-19, remains a global health concern due to its high transmissibility and evolving variants. Although vaccination efforts and therapeutic advancements have mitigated disease severity, emerging mutations continue to challenge diagnostics and containment strategies. As of mid-February 2025, global test positivity has risen to 11%, marking the highest level in over 6 months, despite widespread immunization efforts. Newer variants demonstrate enhanced host cell binding, increasing both infectivity and diagnostic complexity. Objective: This study aimed to evaluate the effectiveness of deep transfer learning in delivering a rapid, accurate, and mutation-resilient COVID-19 diagnosis from medical imaging, with a focus on scalability and accessibility. Methods: An automated detection system was developed using state-of-the-art convolutional neural networks, including VGG16 (Visual Geometry Group network-16 layers), ResNet50 (residual network-50 layers), ConvNeXtTiny (convolutional next-tiny), MobileNet (mobile network), NASNetMobile (neural architecture search network-mobile version), and DenseNet121 (densely connected convolutional network-121 layers), to detect COVID-19 from chest X-ray and computed tomography (CT) images. Results: Among all the models evaluated, DenseNet121 emerged as the best-performing architecture for COVID-19 diagnosis using X-ray and CT images. It achieved an impressive accuracy of 98%, with a precision of 96.9%, a recall of 98.9%, an F1-score of 97.9%, and an area under the curve score of 99.8%, indicating a high degree of consistency and reliability in detecting both positive and negative cases. The confusion matrix showed minimal false positives and false negatives, underscoring the model's robustness in real-world diagnostic scenarios. Given its performance, DenseNet121 is a strong candidate for deployment in clinical settings and serves as a benchmark for future improvements in artificial intelligence-assisted diagnostic tools. Conclusions: The study results underscore the potential of artificial intelligence-powered diagnostics in supporting early detection and global pandemic response. With careful optimization, deep learning models can address critical gaps in testing, particularly in settings constrained by limited resources or emerging variants.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.015
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.647
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.015
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.355
Teacher spread0.319 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it