Critical Insights From FDG PET CT in Diagnosing Delayed Breast Implant-Associated Anaplastic Large Cell Lymphoma Following Textured Implant Recall
Bibliographic record
Abstract
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell lymphoma strongly associated with textured breast implants. This study presents a case of breast implant-associated anaplastic large cell lymphoma in 58-years-old female patient presented with asymmetrical right breast enlargement after 14 years of texture implant recall. MRI of the right breast showed mild thickening of the fibrous capsule surrounding the implant with diffuse asymmetric enhancement. PET-CT demonstrated a small right peri-implant fluid collection with mild FDG uptake in the superior aspect and a mildly hypermetabolic right axillary lymph node. The breast ultrasound revered fluid collection, and 50 mL of straw-colored fluid was aspirated. Cytology of the fluid revealed abnormal cells positive for CD45, CD30, CD3, but negative for CD20. The Ki-67 proliferation index was 20%, and ALK staining was negative indicating anaplastic large cell lymphoma (BIA-ALCL).
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.003 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.004 | 0.002 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".