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Record W4413820105 · doi:10.1038/s41598-025-17004-2

Tracking metal presence in cannabis vaping products from source to inhalation

2025· article· en· W4413820105 on OpenAlexaffabout
Zuzana Gajdosechova, Joshua Marleau-Gillette, Matthew Polivchuk, Ivana Kosarac, Guru Prasad Katuri, Dharani Das, Ashley Cabecinha, Andrew Waye, Hanan Abramovici

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicHeavy Metal Exposure and Toxicity
Canadian institutionsHealth CanadaNatural Resources CanadaNational Research Council Canada
Fundersnot available
KeywordsCannabisTinZincMetalContaminationMaterials scienceCartridgeCopperEnvironmental chemistryMetallurgyChemistryMedicine

Abstract

fetched live from OpenAlex

Vaping cannabis liquids is a convenient method of cannabis consumption, and is considered to be a less harmful alternative to smoking cannabis. However, vaping cannabis carries its own health risks, with many uncertainties, especially concerning the presence of metal particles in vape liquids. The heterogeneous distribution of these particles within the liquid matrix poses analytical challenges in measurement reproducibility. In this study, total metals analysis was performed on five samples from six different legal Canadian cannabis vape liquid products. The results indicated that metals from the vaping device components, cobalt (Co), nickel (Ni), and zinc (Zn) significantly contributed to within-batch variability. In contrast, all analyzed metals showed significant variability among tested products. Single-particle ICP-MS detected metal particles of aluminum (Al), Co, chromium (Cr), copper (Cu), Ni, tin (Sn), and Zn in the vape liquids. To assess potential consumer exposure, cannabis cartridges were vaped using a vaping machine and the resulting aerosol was analyzed. Although the number of detected emitted particles was below the limit of quantitation, all samples produced aerosols containing metal particles of Co, Cr, Ni, lead (Pb), Sn, and Zn. Further analysis using SEM-EDS on the emptied cartridges showed cracking on the connector pin of an unused device, suggesting a potential source of contamination during use and storage. The elemental composition of the metal components in the cartridges matched the detected particles, providing strong evidence that cannabis vape liquids are contaminated by the metal components of vaping devices.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.188
Threshold uncertainty score0.468

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.252
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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