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Record W4413833026 · doi:10.14740/jnr1034

Rapidly Progressive Multifocal Cerebral Vasculitis Presenting With Bi-Hemispheric Stroke

2025· article· en· W4413833026 on OpenAlexvenueno aff
Yiorgos Antoniadis, Chandrika Sanapala, Samir Ruxmohan

Bibliographic record

VenueJournal of Neurology Research · 2025
Typearticle
Languageen
FieldMedicine
TopicVasculitis and related conditions
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineVasculitisCerebral vasculitisStroke (engine)DermatologyPathologyDisease

Abstract

fetched live from OpenAlex

Vasculitis is a rare but important cause of stroke, often presenting with ischemic infarcts due to vascular inflammation and stenosis. While vasculitis-related strokes more commonly occur in younger patients without traditional vascular risk factors, their presentation is highly variable, leading to complex diagnostic and management considerations. Although bi-hemispheric infarcts are often associated with hypercoagulable states or embolic sources, they can also result from vasculitis. We present a unique case of a 38-year-old male with a history of multiple autoimmune conditions who developed rapidly progressive multifocal strokes associated with cerebral vasculitis of uncertain etiology. Despite aggressive medical management, including high-dose corticosteroids, the patient experienced worsening ischemic events and further neurological decline. This case highlights the diagnostic and therapeutic challenges of vasculitis-related stroke, emphasizing the need for early recognition, comprehensive evaluation, and tailored immunosuppressive strategies to improve patient outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.049
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.351
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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