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Record W4413855659 · doi:10.1007/s00394-025-03768-w

Dietary vitamin D and gastric cancer risk within the stomach cancer pooling (stop) project

2025· article· en· W4413855659 on OpenAlexaff
Claudia Santucci, Arianna Natale, Claudio Pelucchi, Rossella Bonzi, Nuno Lunet, Samantha Morais, Jesús Vioqué, Sandra González‐Palacios, Núria Aragonés, Gemma Castaño‐Vinyals, Reza Malekzadeh, Mohammadreza Pakseresht, Eva Negri, Paolo Boffetta, M. Constanza Camargo, María Paula Curado, Zuo‐Feng Zhang, Stefania Boccia, Carlo La Vecchia, Marta Rossi

Bibliographic record

VenueEuropean Journal of Nutrition · 2025
Typearticle
Languageen
FieldMedicine
TopicVitamin D Research Studies
Canadian institutionsUniversity of Alberta
FundersEuropean Regional Development FundFundação para a Ciência e a TecnologiaMinistero dell’Istruzione, dell’Università e della RicercaGeneralitat ValencianaFondazione AIRC per la ricerca sul cancro ETS
KeywordsCancerStomachMedicineStomach cancerGastroenterologyInternal medicinePoolingEnvironmental healthComputer science

Abstract

fetched live from OpenAlex

PURPOSE: The evidence regarding the role of vitamin D on gastric cancer (GC) is controversial. Within the Stomach cancer Pooling (StoP) Project, a global consortium of epidemiological studies on GC, we aimed to evaluate the relationship between dietary vitamin D and GC risk. METHODS: Five case-control studies were included in the analysis, accounting for 1875 cases and 5899 controls. Odds ratios (OR) of GC and the corresponding 95% confidence intervals (CI) for tertiles of vitamin D intake were computed using logistic regression models adjusted for relevant confounders, including energy intake. The pooled ORs were computed using random-effect models. RESULTS: The pooled OR of GC for the highest compared to the lowest tertile of vitamin D intake was 1.06 (95% CI 0.80-1.39), with a p for heterogeneity of 0.019. No significant association was found across strata of sex, age, socioeconomic status, smoking status, alcohol intake, and vegetable and fruit consumption. CONCLUSIONS: Our pooled analysis indicates that there is no association between dietary vitamin D and the risk of GC.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.730
Threshold uncertainty score0.289

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.332
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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