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Record W4413904346 · doi:10.1101/2025.08.27.672658

Value-Added: Importance of Incorporating Menstrual Cycle Phases to Clarify Sex-Related Differences in Force Steadiness

2025· preprint· en· W4413904346 on OpenAlexaff
Chris R. Calkins, Kathryn M. Crosby, Elijah M. K. Haynes, Jennifer M. Jakobi

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldHealth Professions
TopicOccupational Health and Performance
Canadian institutionsUniversity of British Columbia, Okanagan CampusUniversity of British Columbia
Fundersnot available
KeywordsMenstrual cycleValue (mathematics)PsychologyMedicineStatisticsInternal medicineMathematics

Abstract

fetched live from OpenAlex

Abstract Aim This study aimed to determine whether female elbow flexion force steadiness varies across the menses, follicular and luteal phases of the menstrual cycle. Methods To control for repeated testing effects unrelated to hormonal fluctuations across the menstrual cycle, a comparison group of males completed the same protocol over three equally spaced testing sessions to the females. Maximal voluntary contractions and force steadiness were assessed in the neutral and pronated forearm positions. Elbow flexion force tracking tasks were performed at 2.5, 5, 10, 25, 50 and 75% maximal voluntary contraction in both forearm positions, and force steadiness was quantified as the coefficient of variation of force. Results Males were stronger than females (p<0.001), and maximal voluntary contractions did not differ between menstrual phases (p>0.14) or between days in males (p>0.56) in both forearm positions. There was no difference in coefficient of variation of force across sessions for the males (p<0.36). The coefficient of variation of force for all submaximal forces was significantly greater during the luteal phase compared to menses (Neutral p=0.02; Pronated p<0.05) but not the follicular phase (Neutral p=0.71; Pronated p=0.10). The coefficient of variation of force during the luteal phase in females was higher than males in both positions (p<0.02). Conclusion These findings support previous observations that females are less steady than males for isometric steady contractions; however, this study identifies luteal specific phase effects. This underscores the importance of accounting for menstrual cycle phase when conducting sex-related comparisons.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesResearch integrity
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.345
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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