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Antimicrobial Materials Used in Coating Dental Implant Surfaces: State of Art and Future Prospectives

2025· preprint· en· W4413935111 on OpenAlexfundno aff
Kazi Naziba Tahsin, Amin S. Rizkalla, Paul A. Charpentier

Bibliographic record

VenuePreprints.org · 2025
Typepreprint
Languageen
FieldEngineering
TopicBone Tissue Engineering Materials
Canadian institutionsnot available
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsCoatingAntimicrobialDental implantMaterials scienceDentistryImplantNanotechnologyMedicineChemistry

Abstract

fetched live from OpenAlex

This review presents a comprehensive overview of dental materials that support tissue healing while exhibiting antimicrobial properties. Emphasis is placed on materials that are biocompatible, bioactive, and non-toxic to host cells, with demonstrated bacteriostatic and bactericidal activity. The review summarizes current research on natural bactericides, antimicrobial polymers, and bioactive glass/polymer composites, along with various techniques employed for surface coating of dental implants. Three principal categories of antimicrobial coatings have been identified: antibacterial phytochemicals, synthetic antimicrobial agents (including polymers and antibiotics), and metallic nanoparticles. Among these, antibacterial peptide-based coatings have been the most extensively studied and have shown the greatest effectiveness in reducing bacterial colonization, especially during extended incubation periods. These coatings offer high antimicrobial potency, durability, and excellent biocompatibility, positioning them as promising candidates for long-term protection against microbial contamination. However, additional in vitro and pre-clinical studies are warranted to thoroughly evaluate their therapeutic potential and to establish their efficacy and safety for clinical applications in the prevention of peri-implant infections.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.117
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.271
Teacher spread0.246 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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