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Record W4413971114 · doi:10.1016/j.ibneur.2025.08.011

Research hotspots and trends in the interaction mechanisms of neuroinflammation and sleep disorders: A bibliometric analysis based on WOS

2025· article· en· W4413971114 on OpenAlexaboutno aff
Nan Zhao, Zhaoqiong Zhu, Qihai Gong, Rui Jiang

Bibliographic record

VenueIBRO Neuroscience Reports · 2025
Typearticle
Languageen
FieldNeuroscience
TopicTryptophan and brain disorders
Canadian institutionsnot available
FundersDalian Medical UniversityHealth Commission of Guizhou Province
KeywordsBibliometricsData scienceNeuroinflammationGeographyComputer scienceLibrary scienceMedicine

Abstract

fetched live from OpenAlex

This study aims to analyze the research hotspots and trends regarding neuroinflammation in sleep disorders over the past 30 years through bibliometric and review analyses. Relevant publications were sourced from the Web of Science Core Collection (WoSCC). We utilized VOSviewer and CiteSpace for the visualization and quantitative analysis of the literature to provide an objective presentation and predictions. A total of 2545 publications related to neuroinflammation and sleep disorders were identified, with the overall number of publications showing a continuous upward trend. Most of the publications originated from the United States and China. The University of Toronto, Harvard Medical School, and the University of California, Los Angeles, are leading institutions in this field. David Gozal and Michael R. Irwin are recognized as prominent figures in this area. The International Journal on Molecular Sciences and Brain Behavior and Immunity are the journals with the highest publication volume. Keywords and clustering analyses indicate that the current research in this field has developed a multidisciplinary integration pattern, with core trends focusing on the multi-axis regulation of neuroimmune interaction mechanisms, as well as individualized targeted intervention strategies based on biomarkers and gene editing. Additionally, the development of emerging technologies such as organoids and the establishment of multidisciplinary collaborative networks bring new hope for exploring the interactions between neuroinflammation and sleep disorders.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.043
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Bibliometrics
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.991
Threshold uncertainty score0.049

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.043
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.004
Bibliometrics0.1900.201
Science and technology studies0.0010.001
Scholarly communication0.0050.004
Open science0.0010.003
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.360
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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Same venueIBRO Neuroscience ReportsSame topicTryptophan and brain disordersFrench-language works237,207