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Record W4413971299 · doi:10.1590/1519-6984.296244

Stimulation of the production of proteases from Penicillium verrucosum isolated from Egyptian soil

2025· article· en· W4413971299 on OpenAlexaff
A A Garziz, Mohamed Mahmoud Helal, Ahmed Younis, Mohamed A. El‐Badry, Mohammed Yosri

Bibliographic record

VenueBrazilian Journal of Biology · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEnzyme Production and Characterization
Canadian institutionsMinistry of Health and Long Term Care
Fundersnot available
KeywordsProteaseProteasesBiologyEnzymeFilamentous fungusFungusFood scienceBiochemistryMicrobiologyBotany

Abstract

fetched live from OpenAlex

The uses of proteolytic enzymes in manufacturing procedures are numerous. Researchers are investigating a number of strategies to find, rework, or artificially produce enzymes with improved suitability for manufacturing processes in light of the growing needs and uses. Alkaline protease production was assessed in fungal strains that were obtained from soil using the serial dilution technique. Using molecular techniques, the isolate with the greatest potential for producing enzymes was identified. Gel filtering was used to purify the enzyme. In order to enhance fugus ability to generate protease under various growth conditions, this investigation explains how to optimize a culture medium. The fungus with the highest probability was identified as Penicillium verrucosum with accession number PV529631. The purified homodimer protein for purified protease was assessed to have two peaks at 42.5 kDa and 83.7 kDa, consequently upon screening at 280 nm. The optimal culture conditions have been detected upon culture for the isolated fungus at pH =9, temperature = 35 °C, using sucrose as a carbon source, insertion of peptone as a nitrogen and using Soy cake as waste material for culture conditions. The results of the research demonstrate the P. verrucosum strain's capacity to produce the protease enzyme. To fully use the possibilities of these substrates and promote the creation of superior and effective hydrolytic enzymes, it is imperative to keep investigating and refining these approaches.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.075
Threshold uncertainty score0.257

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.247
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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