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Record W4413981167 · doi:10.12688/hrbopenres.14202.1

The global impact of COVID-19 control measures on people with dementia living at home and their carers during the two first waves: A systematic review of quantitative and qualitative research across 27 countries

2025· article· en· W4413981167 on OpenAlexafffund
Yaohua Chen, Tatyana Mollayeva, Rachel Fitzpatrick, Thaisa Tylinski Sant’Ana, Francesca R Farina, Dorota Świątek, Kelli Sopidou, Evelyn Tabilo, Marta Maria Betka, Iracema Leroi, Tomás Léon, Geeske Peeters

Bibliographic record

VenueHRB Open Research · 2025
Typearticle
Languageen
FieldHealth Professions
TopicGeriatric Care and Nursing Homes
Canadian institutionsToronto Rehabilitation InstituteUniversity of Toronto
FundersCanadian Institutes of Health ResearchCanada Research ChairsPublic Health Agency
KeywordsCoronavirus disease 2019 (COVID-19)DementiaQualitative researchGerontology2019-20 coronavirus outbreakPsychologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineSociologyVirologySocial scienceDiseasePathology

Abstract

fetched live from OpenAlex

<ns3:p>Background COVID-19 control measures have had a unique impact on people with dementia (PWD) and their carers living at home. Yet, uncertainty exists regarding the global impact of such measures, and whether differences exist between countries and global regions. We aimed to synthesize evidence on this topic. Methods We searched Medline, PsycINFO, EMBASE, Web of Science, CINAHL, Latin American and Caribbean Health Literature (Lilacs), Scientific Electronic Library online (Scielo), and EM Premium, from the start of the pandemic to July 2022. At least two researchers independently screened citations and performed quality assessment following recommended criteria for critical appraisal according to study methodology. We analyzed data by country and region, and synthesized results descriptively. Results Sixty-nine studies met inclusion criteria (74% qualitative and 26% quantitative; 22% included PWD, 44% carers of PWD, 4% dyads), with a total of 209,738 participants. Most studies were conducted in Europe (59%), followed by Asia and North America (15% each), South America (7%) and Oceania (1%). Two studies presented data from multiple regions (3%). The quality of the studies varied, with the majority (62%) being of moderate quality. Across the study populations and global regions, COVID-19 control measures had implications for PWD and carers’ access to health services, physical and mental health and daily routine, cognition, behaviour, with accompanying social and economic costs. Conclusion Our results highlight how public health measures impacted PWD and their carers living at home globally, and suggest the need for proactive planning of preventive measures to mitigate the negative impact, in anticipation of future public health threats. Other This work was funded by the JPND Call for Expert Working Groups: The Impact of COVID-19 on Neurodegenerative Diseases in partnership with the CIHR-Institute of Aging; Public Health Agency (CIHR #02342-000). PROSPERO CRD42024554701.</ns3:p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.032
metaresearch head score (Gemma)0.011
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.227
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0320.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0040.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.176
GPT teacher head0.596
Teacher spread0.420 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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