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Record W4413992591 · doi:10.12669/pjms.41.9.11726

Exploring the Socio-cultural Dynamics of Treatment Adherence amongst Females living with Pulmonary Tuberculosis in Karachi, Pakistan

2025· article· en· W4413992591 on OpenAlexaff
Mehjabeen Musharraf, Lubna Baig

Bibliographic record

VenuePakistan Journal of Medical Sciences · 2025
Typearticle
Languageen
FieldMedicine
TopicTuberculosis Research and Epidemiology
Canadian institutionsShared Health
Fundersnot available
KeywordsMedicinePulmonary tuberculosisTuberculosisGerontologyPathology

Abstract

fetched live from OpenAlex

Background & Objective: Pakistan ranks fifth amongst thirty high-burden TB countries and fourth-highest in prevalence of multi-drug resistant TB. Despite higher TB rates among men, women disproportionately experience unsuccessful treatment outcomes. The National TB-Control Program despite its contributions has not adequately addressed underlying grassroots factors, particularly those impacting women, that contribute to poor treatment-outcomes. Thus the objective is to explore socio-cultural and grassroots factors influencing treatment non-adherence amongst females living with Pulmonary TB. Methods: A qualitative Phenomenological design was adopted. Twelve in-depth interviews were conducted at a TB Clinic in Karachi (from February to May 2020) with participants including (i) females living with Pulmonary TB and (ii) healthcare providers engaged in TB service-provision. Interviews were semi-structured and conducted in-person. Data was analyzed inductively using thematic analysis. Results: Three themes contributing to treatment non-adherence emerged, which are: A) The burden of home-making with sub-themes of a culture of matriarchy, traditional household norms, and intended non-disclosure of TB status; B) The journey of pursing treatment with subthemes of challenges in accessing diagnostic services, barriers in treatment adherence/continuation, unique treatment-related misconceptions; and C) TB myths with subthemes emphasizing local rumors and an inherent lack of trust in public healthcare services. Conclusion: This study reveals important grassroots, socio-cultural and physical barriers to treatment adherence among women, including gender, social norms and treatment demands. Addressing these requires a holistic approach prioritizing community empowerment with a focus on understanding day-to-day lived experiences of TB and enhancing healthcare provider capacity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.061
Threshold uncertainty score0.648

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.401
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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