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Record W4414019407 · doi:10.1002/ijgo.70500

Reducing post‐cesarean sepsis: Current best practice in prevention and treatment

2025· article· en· W4414019407 on OpenAlexaff
Amanda Lazzaro, Gauri Karandikar, María da Luz Martins, Friday Saidi, David M. Aronoff, Eliana Amaral, Isabelle Boucoiran, Mandakini Megh, Bo Jacobsson, Edgar Ortíz, Deborah Money, Dharmintra Pasupathy, Edward Buga

Bibliographic record

VenueInternational Journal of Gynecology & Obstetrics · 2025
Typearticle
Languageen
FieldMedicine
TopicMaternal and Perinatal Health Interventions
Canadian institutionsUniversity of British ColumbiaUniversité de Montréal
Fundersnot available
KeywordsMedicineSepsisPregnancyObstetricsAntibiotic prophylaxisIncidence (geometry)ComplicationIntensive care medicineAntibioticsSurgery

Abstract

fetched live from OpenAlex

Cesarean section is the most common surgical procedure performed worldwide. It is associated with good perinatal and maternal outcomes when indicated. The rising global cesarean birth rate has coincided with an increase in post-cesarean sepsis - specifically site infections, which have an incidence of 7% worldwide. Post-cesarean sepsis remains a serious complication that prolongs hospital stays, resulting in additional surgery and worsening maternal morbidity and mortality, and increasing healthcare costs with socioeconomic consequences. There is no global practice guide for post-cesarean sepsis, despite most maternal deaths due to sepsis occurring postpartum. Here we introduce a FIGO Committee on Infections During Pregnancy guide on prevention and treatment of post-cesarean sepsis. We encourage strategies to keep cesarean birth rates at evidence-based levels by aiming to standardize the management of labor and to increase the percentage of vaginal births after a previous cesarean. Identification of risk factors before and during the surgery is the primary step towards prevention. These measures, combined with evidence-based strategies to promote infection prevention practices, including routine prophylactic antibiotics, skin and vaginal preparation before cesarean birth, and glove change prior to skin closure, contribute towards reducing maternal morbidity and mortality.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.020
metaresearch head score (Gemma)0.048
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.020
Threshold uncertainty score0.107

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0200.048
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0030.003
Science and technology studies0.0010.002
Scholarly communication0.0050.003
Open science0.0040.003
Research integrity0.0060.009
Insufficient payload (model declined to judge)0.0080.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.406
Teacher spread0.373 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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