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Record W4414033801 · doi:10.1111/nph.70521

Genetic architecture of the <i>S</i> ‐locus supergene revealed in a tetraploid distylous species

2025· article· en· W4414033801 on OpenAlexaff
Zhonglai Luo, Spencer C. H. Barrett, Tieyao Tu, Zhongtao Zhao, Shanshan Jia, Shiran Gu, Tingting Duan, Yu Zhang, Bingqiang Xu, Lei Gu, Xiaofang Deng, Libo Jiang, Miaomiao Shi, Dianxiang Zhang

Bibliographic record

VenueNew Phytologist · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicChromosomal and Genetic Variations
Canadian institutionsUniversity of Toronto
FundersNational Natural Science Foundation of China
KeywordsBiologySupergene (geology)Locus (genetics)Genetic architectureEvolutionary biologyBotanyGeneticsEcologyGeneQuantitative trait locus

Abstract

fetched live from OpenAlex

Summary Heterostyly is a polymorphic floral adaptation controlled by supergenes. The molecular basis of distyly has been investigated in diploid species from several unrelated families, but information is lacking for polyploid systems. Here, we address this knowledge gap in Schizomussaenda henryi , a tetraploid distylous species of Rubiaceae, the family with the greatest number of heterostylous species. Using chromosome‐level genome assemblies and transcriptome profiling, we characterized its tetraploid genome, identified the S ‐locus region, and performed evolutionary analysis. The S ‐locus contains four hemizygous genes in the S‐morph. SchzAUX22 emerged as a candidate gene potentially regulating both style length and filament growth via auxin signaling. Phylogenetic and k ‐mer‐based analysis suggested a hybrid allopolyploid origin for S. henryi , while no subgenome dominance was detected. Results from the comparison of K s values indicated that S ‐locus formation likely occurred through stepwise duplications. This study provides the first comprehensive genomic analysis of distyly in a polyploid species and demonstrates that the S ‐locus remains intact despite allopolyploidization resulting from hybridization. Our results indicated that polyploidization does not necessitate the breakdown of distyly, which occurs in several other heterostylous lineages.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.207
Teacher spread0.196 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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