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Record W4414049947 · doi:10.1093/dote/doaf061.223

364. IMPROVING PRE-OPERATIVE EMOTIONAL DISTRESS SHORTENS HOSPITALIZATION FOR ESOPHAGECTOMY

2025· article· en· W4414049947 on OpenAlexaff
Jin Kweon, Mehrnoush Dehghani, Lorenzo Ferri, Sara Najmeh, Carmen Mueller, Jonathan Cools-Latrigue, Jonathan Spicer, Trafford Crump

Bibliographic record

VenueDiseases of the Esophagus · 2025
Typearticle
Languageen
FieldMedicine
TopicEsophageal Cancer Research and Treatment
Canadian institutionsMcGill University Health CentreMcGill University
Fundersnot available
KeywordsEmotional distressEsophagectomyEsophageal cancerReferralDistressTest (biology)Retrospective cohort studyTertiary referral hospital

Abstract

fetched live from OpenAlex

Abstract Background Pre-operative emotional distress—characterized by anxiety, depression, and/or psychological stress—is commonly experienced by patients diagnosed with esophageal cancer. Previous studies have observed that emotional distress is associated with longer hospital length of stays (LOS) in various cancer populations, including esophageal cancer. However, the impact of changes in emotional distress during the pre-operative period on post-operative LOS remain unclear. This exploratory study aims to test whether improvements in pre-operative emotional distress influence post-esophagectomy LOS. Methods We conducted a retrospective analysis using data collected from a high volume North American tertiary care referral centre. Eligible participants completed the Functional Assessment of Cancer Therapy-Esophageal (FACT-E) at (1) diagnosis and (2) prior to esophagectomy. Emotional distress was measured using the FACT-E Emotional Well-Being (EWB) subscale. Changes in EWB scores between the two time points were categorized as ‘improved’ or ‘unimproved’ (i.e., stable or decreased). The Mann–Whitney U test was used to test the associations between LOS and the ‘improved’/‘unimproved’ EWB category. Results Of the 106 participants that completed the FACT-E at both time points and had an LOS related to esophagectomy, 67 (63%) were categorized as ‘improved’. Those in the ‘improved’ category experienced an average increase of 5.1 points in the EWB subscale score. The ‘improved’ group had an average LOS of 9.2 days compared to 10.4 days for the ‘unimproved’ group (p < 0.05). Conclusion Improvements in EWB score—used as a proxy for emotional distress—during the pre-operative period was associated with shorter postoperative LOS for esophageal cancer patients. The average difference was more than a full day. This suggests that emotional distress, if improved, can directly influence early outcomes and post-esophagectomy recovery. Future research should investigate the impact of pre-operative psychological assessments and interventions to better understand emotional distress as a modifiable risk factor for esophagectomy outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.319
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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