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Record W4414068079 · doi:10.31083/rn38630

Effects of Diabetes Mellitus on Motor and Non-Motor Symptoms in Parkinson’s Disease: A Cross-Sectional Study

2025· article· en· W4414068079 on OpenAlexaboutno aff
Irving Christian Rodríguez-González, Fernando Botello-Villagrana, Sergio Ruben Gomez-Villalobos, Ximena M. Torres-Mancilla, Arnulfo González‐Cantú, Mirna González‐González, Daniel Martínez-Ramírez

Bibliographic record

VenueRevista de Neurología · 2025
Typearticle
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsDiabetes mellitusDiseaseMotor activityType 1 diabetesPopulation

Abstract

fetched live from OpenAlex

Introduction: While there is a growing body of evidence indicating a potential connection between Parkinson’s disease and diabetes mellitus, there is a lack of focus on investigating how diabetes correlates with the severity of both motor and non-motor symptoms in Parkinson’s disease. Objective: This study examined and contrasted both motor and non-motor symptoms in patients diagnosed with Parkinson’s disease, stratified by the presence or absence of diabetes. Methods: A total of 40 Parkinson’s disease patients, divided into two groups (with and without diabetes), were assessed using various scales, including the Movement Disorders Society – Unified Parkinson’s Disease Rating Scale, Scales for Outcomes in Parkinson’s Disease - Autonomic Dysfunction and Non-Motor Symptoms, Beck Depression Inventory, Montreal Cognitive Assessment, and Parkinson’s Disease Questionnaire-39. Demographic and clinical characteristics were also recorded. Statistical analyses included t-tests, Mann-Whitney U tests, and Fisher’s exact test. Results: Significant differences were observed in the motor sub-score of postural instability and gait disturbance symptoms, autonomic total scores, urinary function domain, depression scores, and quality of life in the mobility and emotional domains between the Parkinson’s disease non-diabetes, and Parkinson’s disease - diabetes groups. Conclusions: Our study unveiled differences in motor and Non-Motor Symptoms among patients with Parkinson’s disease and diabetes, underscoring the influence of diabetes on manifestations of the disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.747

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.270
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

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