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Record W4414147113 · doi:10.1002/jcv2.70140

Early joint attention abilities measured by the ADOS-2 predict subsequent expressive language development in minimally verbal autistic children

2025· preprint· en· W4414147113 on OpenAlexfundno aff
Tanya Nitzan, Moran Naama Bachrach, Michal Ilan, Michal Faroy, Danel Waissengreen, Analya Michaelovsky, Dikla Zagdon, Yair Sadaka, Omer Bar Yosef, Ditza A. Zachor, Einat Avni, Idan Menashe, Gal Meiri, Judah Koller, Ilan Dinstein

Bibliographic record

VenueJCPP Advances · 2025
Typepreprint
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsnot available
FundersAzrieli Foundation
KeywordsJoint attentionExpressive languageLanguage developmentLogistic regressionCognitionAffect (linguistics)Expressive SuppressionLanguage delay

Abstract

fetched live from OpenAlex

Abstract Background Most preschool autistic children exhibit substantial language delays, yet only ∼25% remain minimally verbal (MV) throughout life. Developing expressive language is crucial for improving outcomes. This study examined early predictors of later expressive language growth in MV preschool autistic children. Methods Data from 99 MV autistic children (mean age 27.7 months at diagnosis) who completed ADOS‐2 assessments at diagnosis and 12–24 months later were analyzed. Children were stratified into three groups according to their language abilities at follow‐up (MV, one‐word, and phrases). Logistic regression was used to determine whether baseline ADOS‐2 calibrated severity scores (CSS), non‐verbal cognitive abilities, or Joint Attention (JA), derived from six ADOS‐2 items, enabled prediction of expressive language abilities at follow‐up. Results Children who successfully developed expressive language (one‐word/phrases) had significantly lower baseline ADOS‐2 social affect CSS and JA scores, but did not differ in their non‐verbal cognitive abilities or ADOS‐2 restricted and repetitive behaviors CSS. Gains in JA were significantly larger in children who developed expressive language. Conclusion MV preschoolers with better social abilities at diagnosis, specifically JA, were more likely to develop expressive language within 1–2 years. Joint attention scores derived from the ADOS‐2 offer an easily accessible and widely available measure with important prognostic value for MV children.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.538
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.291
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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