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Record W4414182109 · doi:10.1186/s12982-025-00904-z

Impact of pharmacist-led interventions on pregnancy-related health outcomes: a systematic review

2025· article· en· W4414182109 on OpenAlexaboutno aff
Chia Siang Kow, Venus Sing Yee Lee, G. André Ng, Jing Wei Teoh, Kan Yin Wong, E Lyn Lee, Kaeshaelya Thiruchelvam

Bibliographic record

VenueDiscover Public Health · 2025
Typearticle
Languageen
FieldMedicine
TopicPregnancy and Medication Impact
Canadian institutionsnot available
Fundersnot available
KeywordsPsychological interventionObservational studyPregnancyAdverse effectMEDLINEPharmacistSystematic reviewGestational diabetesHealth care

Abstract

fetched live from OpenAlex

Pharmacist-led interventions are crucial for improving healthcare outcomes, particularly for pregnant women who face unique medication-related risks. Effective medication management during pregnancy directly impacts maternal and neonatal health, reducing medication errors and adverse drug reactions due to physiological changes and the need to avoid teratogenic substances. This review aimed to systematically evaluate the impact of pharmacist-led interventions on medication adherence, clinical outcomes, and maternal or neonatal health among pregnant women. Following PRISMA guidelines, a comprehensive search of PubMed, Embase, and Scopus was conducted to identify studies from 2013 to 2023 on pharmacist-led interventions in pregnant women. Randomized controlled trials, quasi-experimental studies, and observational studies were included. Data were extracted using a standardized form, and study quality was assessed with Cochrane ROB 2, ROBINS-I, and modified Newcastle-Ottawa Scale. Seven studies from Canada, Australia, Indonesia, Norway, Nigeria, and China were included. Pharmacist interventions, such as medication therapy management, patient education, and the identification of drug interactions, significantly improved medication adherence, clinical outcomes, and patient satisfaction. These interventions were particularly effective in managing hypertensive disorders, asthma, and gestational diabetes mellitus, leading to better health outcomes and fewer adverse events. Pharmacist-led interventions significantly improve health outcomes for pregnant women by enhancing medication adherence and clinical care. Further research is needed to confirm these benefits, standardize outcomes, and explore additional areas of impact to optimize maternal and neonatal health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.926
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.095
GPT teacher head0.489
Teacher spread0.394 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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