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Can Measures Of Stepping Provide Insight Into Fitness And Health For Individuals With Breast Cancer?

2025· article· en· W4414232252 on OpenAlexaffabout
Charles E. Matthews, Jeff K. Vallance, Jessica McNeil, Chad W. Wagoner, Qinggang Wang, Leanne Dickau, Margaret L. McNeely, S. Nicole Culos‐Reed, Lin Yang, Kerry S. Courneya, Christine M. Friedenreich

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2025
Typearticle
Languageen
FieldMedicine
TopicCancer survivorship and care
Canadian institutionsUniversity of CalgaryUniversity of AlbertaAlberta Health ServicesAthabasca University
Fundersnot available
KeywordsBaseline (sea)Breast cancerLogistic regressionOddsPhysical fitnessQuality of life (healthcare)Longitudinal studyCancer stage

Abstract

fetched live from OpenAlex

PURPOSE: Step-based measures recorded in daily life may help identify individuals with cancer who have low fitness levels and poor health—information that could aid health care providers in optimizing care. Thus, we examined links between low step counts and intensity (cadence, peak steps) and lower health-related fitness and patient reported health. METHODS: The Alberta Moving Beyond Breast Cancer Study enrolled 1,528 individuals newly diagnosed with breast cancer and measured 5 components of health-related fitness (12 measures), and patient reported health (9 indicators) near diagnosis, and one-year later. Step counts and intensity were measured at baseline using activPAL (7-days). Logistic regression estimated cross-sectional associations (odds ratios; OR) at baseline, and prospectively between lower quintiles of baseline stepping and low fitness and poorer health at one year, adjusting for age, demographics, height, weight, and cancer diagnosis/treatment. RESULTS: At baseline 1,408 individuals with breast cancer (mean age 56 yrs; early stage (90%)) provided valid activPAL measures (mean 14.8 hrs/d, 5.5 days of wear). Taking <5,000 steps/d (lower quintile) at baseline was associated with low fitness (9 of 12 measures) and poorer health (8 of 9 indicators) at baseline and remaining in low fitness (7 of 12 measures) and poorer health (5 of 9 indicators) one year later. Taking <5,000 steps/d at baseline was significantly associated with greater odds of moving from favorable to unfavorable/low fitness and poorer health categories one year later (VO2peak (OR = 2.6), curl ups (OR = 1.8), chest endurance (OR = 2.4), self-reported health (OR = 2.4), physical quality of life (OR = 2.1), fatigue (OR = 1.8)). Preferred cadence and peak stepping were inconsistently associated after adjustment for total steps. CONCLUSIONS: Easily obtained step counts measured near diagnosis could facilitate wellness planning across the treatment timeline and into survivorship for individuals with breast cancer. Supported by: Canadian Institutes of Health Research (Awards: 107534, 155952, 159927)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score0.087

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.320
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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