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Record W4414242731 · doi:10.1177/09727531251369164

Cognitive Functions in High-altitude Tribal Population: Assessment Using the Montreal Cognitive Assessment (MoCA) Tool

2025· article· en· W4414242731 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueAnnals of Neurosciences · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHigh Altitude and Hypoxia
Canadian institutionsnot available
Fundersnot available
KeywordsMontreal Cognitive AssessmentCognitionCognitive Assessment SystemEffects of sleep deprivation on cognitive performanceCognitive agingCognitive decline

Abstract

fetched live from OpenAlex

Background High altitude (HA) environments expose individuals to chronic hypoxia, which can affect cognitive function. While studies have explored cognitive deficits in lowlanders ascending to HAs, there is limited research on cognitive function among natives of HA. Purpose This study aimed to evaluate cognitive functions in the tribal population of Himachal Pradesh India using the Montreal Cognitive Assessment (MoCA) tool and assess the effect of high and very HAs along with age and gender variation in cognitive functions in these HA natives. Methods This study included 359 participants who lived at HAs. Cognitive function was assessed using MoCA. Participants were stratified by altitude (3,000–3,500 m and >3,500 m) and age group (20–40, 41–60 and >60 years). Appropriate statistical analyses were performed to determine the association of altitude, age, and sex with MoCA total and subscale scores. Results Significant associations were found between altitude and performance on the Naming, Attention, Delayed Recall, and Orientation subscales ( p < .001, p < .001, p < .001 and p = .002, respectively). Specifically, a significant age-related decline was observed across the MoCA total score and most subscales ( p < .001, Kendall’s Tau = 0.48). Gender also had a significant association with the Visuospatial/Executive and Attention subscales ( p < .001 for both), with males scoring higher than females. Conclusion Increasing altitude was associated with lower scores on specific cognitive domains. Age is a primary factor influencing cognitive performance in high-altitude natives and is associated with lower MoCA scores. Gender differences were also observed in specific cognitive functions. These findings suggest that altitude, age, and sex play important roles in shaping the cognitive profiles of individuals living at HAs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.281
Threshold uncertainty score0.385

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.384
Teacher spread0.333 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it