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Record W4414258244 · doi:10.1101/2025.09.11.25335505

Habit Reversal Training for Tic Disorders: Clinical Outcomes from a Large Sample of Youth and Adults Treated with Therapist-delivered Video Therapy

2025· preprint· en· W4414258244 on OpenAlexaff
Jamie D. Feusner, Clare Beatty, Patrick B. McGrath, Nicholas R. Farrell, Mia Nuñez, Nicholas Lume, Stephen M. Smith, Andreas Rhode

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldPsychology
TopicObsessive-Compulsive Spectrum Disorders
Canadian institutionsUniversity of TorontoCentre for Addiction and Mental Health
Fundersnot available
KeywordsObservational studyIntervention (counseling)Session (web analytics)HabitNaturalistic observationTelemedicineRandomized controlled trialSample (material)Augment

Abstract

fetched live from OpenAlex

Abstract Tic disorders, including persistent motor and vocal tic disorders and Tourette syndrome, are neurodevelopmental conditions affecting youth and adults. Habit reversal training (HRT) is a behavioral intervention with demonstrated efficacy from in-person studies, but little information exists about its effectiveness as a remotely-delivered treatment. We examined the effectiveness of therapist-delivered video therapy (HRT) with digital support across the lifespan in a sample of 167 patients with tic disorders (76 children, 38 adolescents, 53 adults). HRT sessions were delivered as one-on-one therapist-delivered video HRT with between-session support including messaging with the therapist, digital support tools, and an online peer community. Tic clinical assessments were administered at baseline, near sessions 7 and 14, and the final treatment session. At session 14, tic symptoms showed a median 39.0% severity reduction (youth: 40.9%; adults: 38.1%). Improvements were maintained through the final treatment sessions, with a median reduction of 44.4% from baseline (youth: 43.5%; adults: 55.4%). This observational analysis demonstrates that therapist-delivered video HRT can effectively reduce tic severity, with maintenance and further improvement of symptoms over an extended treatment duration, in a real-world setting. The virtual delivery format may help address barriers to accessing evidence-based care for tic disorders across the lifespan. Strengths and limitations of this study Large naturalistic sample (N=167) provides real-world effectiveness data for therapist-delivered video HRT across developmental stages from children to adults Video therapy format with digital support eliminates geographical barriers while allowing treatment delivery in patients’ natural environments Retrospective observational design without control group precludes causal inferences about treatment effectiveness compared to alternative interventions Self-report and parent-report outcome measures may introduce reporting bias Validated clinical response thresholds are available only for youth measures (PTQ) but not for adult measures (ATQ), limiting interpretation of treatment response rates across age groups

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.049
GPT teacher head0.343
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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