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Record W4414273260 · doi:10.1101/2025.09.16.676299

Fine Motor Serious Game Training Improves Gait in Parkinson’s Disease: A Pilot Study

2025· preprint· en· W4414273260 on OpenAlexaff
Valentin Bégel, Frédéric Puyjarinet, Christian Gény, Valérie Cochen De Cock, Serge Pinto, Simone Dalla Bella

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldPsychology
TopicChildren's Physical and Motor Development
Canadian institutionsUniversité de MontréalCentre for Research on Brain Language and MusicInternational Laboratory for Brain, Music and Sound Research
FundersInstitut Universitaire de France
KeywordsCadenceGaitRandomized controlled trialTelerehabilitationGross motor skillGait trainingVideo gameTraining (meteorology)

Abstract

fetched live from OpenAlex

Abstract Crucial functions for human behavior such as gross motor skills (e.g., walking), cognitive, rhythmic, and fine motor processes are mostly considered unrelated. However, these functions may interact, but their relations are still poorly understood. Moreover, evidence of causal links between them is scarce. Neurological disorders such as Parkinson’s Disease affect all these functions and thus provide a model to study the interplay between them. We tested the effect of a training delivered using serious games on tablet, involving upper limb rhythmic and fine motor functions, on walking capacities in patients with Parkinson’s Disease (PwPD). PwPD gathered into an Intervention group played either a rhythm game, or an adaptation of Tetris , four times a week for six weeks. Before and after the training, gait was evaluated in spontaneous walking and a dual task (counting backward while walking). A Control group of participants did not receive any training. Gait speed, stride length and cadence improved in the Intervention group after the training in comparison with the Control group. The improvement was observed in both Intervention groups, in the spontaneous and in the dual-task conditions. These findings support the hypothesis that gross (axial) motor functions can be trained by fine (lateralized) motor training administered via serious games, possibly by stimulating the rhythmic, perceptual, and cognitive resources sensory systems. This opening promising perspectives for telerehabilitation. Patients with movement disorders could benefit from this promising low-cost and engaging training method, fostering inclusivity and autonomy for people who have reduced access to the clinic.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: Non-randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.256
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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