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Record W4414307880 · doi:10.1080/01676830.2025.2553661

Implant extrusion after eye removal for endophthalmitis and panophthalmitis

2025· review· en· W4414307880 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueOrbit · 2025
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicOcular Disorders and Treatments
Canadian institutionsUniversity of WindsorDalhousie University
Fundersnot available
KeywordsEndophthalmitisComplicationImplantProspective cohort studyAntibioticsExtrusion

Abstract

fetched live from OpenAlex

PURPOSE: To evaluate the rate of orbital implant extrusion and exposure following enucleation or evisceration in patients with endophthalmitis or panophthalmitis, and to assess the influence of infectious etiology, implant type, and surgical technique on extrusion risk. METHODS: A systematic review was conducted using MEDLINE, CINAHL, Embase, and Scopus for studies published between January 1980 and December 2024. Studies were included if they evaluated implant extrusion or exposure following eye removal surgery in patients diagnosed with endophthalmitis or panophthalmitis. Fourteen retrospective cohort studies met the inclusion criteria. RESULTS: Extrusion or exposure rates ranged from 0% to 53%. Pseudomonas aeruginosa was the most frequently implicated pathogen. Non-porous implants, especially silicone, were more commonly associated with extrusion, while porous implants, particularly hydroxyapatite, demonstrated lower complication rates. No clear difference was observed between evisceration and enucleation in terms of extrusion risk. CONCLUSIONS: Implant extrusion is a significant postoperative complication in the setting or endophthalmitis or panophthalmitis. Pseudomonas aeruginosa and the use of non-porous implants may increase extrusion risk. The use of porous implants and appropriate prophylactic antibiotics may be associated with lower risk of extrusion. Further prospective studies are required to standardize risk assessment and prevention strategies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.994
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.312
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it