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Record W4414329371 · doi:10.1128/mra.00641-25

Complete genome sequences of two <i>Treponema pallidum</i> subsp. <i>pallidum</i> specimens from Canadian patients

2025· article· en· W4414329371 on OpenAlexaffabout
Nishant Singh, Thomas Braukmann, Mackenzie Neale, George S. Long, Derek R. Stein, Paul Van Caeseele, Keith D. MacKenzie, Jessica Minion, Gary Van Domselaar, Morag Graham, Andrea D. Tyler, Samir N. Patel, Venkata R. Duvvuri, RSW Tsang

Bibliographic record

VenueMicrobiology Resource Announcements · 2025
Typearticle
Languageen
FieldMedicine
TopicSyphilis Diagnosis and Treatment
Canadian institutionsProvincial Laboratory of Public HealthPublic Health Agency of CanadaYork UniversityUniversity of TorontoPublic Health Ontario
Fundersnot available
KeywordsGenomeWhole genome sequencingGenetic diversityGenomicsDNA sequencingHuman genomePublic health

Abstract

fetched live from OpenAlex

ABSTRACT We report the genome sequences of two Treponema pallidum subsp. pallidum specimens in Canada, with basic details on the genetic diversity and antimicrobial resistance. This data contributes to the understanding of T. pallidum evolution and epidemiology, supporting syphilis surveillance and public health efforts.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.120
Threshold uncertainty score0.242

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.003
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.257
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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