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Abstract IA002: Full circle: Return of value to ovarian cancer research participants, advocates, and survivors

2025· article· en· W4414349247 on OpenAlexaff
Celeste Leigh Pearce, Gillian E. Hanley, Anne Chase, Cindy McKinnon Deurloo, Jean L. Richardson, Bronwyn Grout

Bibliographic record

VenueCancer Research · 2025
Typearticle
Languageen
FieldMedicine
TopicAdvances in Oncology and Radiotherapy
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsValue (mathematics)Survivorship curveLiteracyMultidisciplinary approachReading (process)Process (computing)Health literacySelection (genetic algorithm)Disease

Abstract

fetched live from OpenAlex

Abstract Survival and survivorship research in ovarian cancer has generated vital insights that can significantly impact the lives of people with the disease and their communities. However, there are persistent challenges in ensuring that research findings are effectively disseminated back to the individuals who contribute to and are most affected by this work. In the Multidisciplinary Ovarian Cancer Outcomes Group (MOCOG) study, engagement with patient advocates has highlighted an urgent need for accessible, understandable dissemination materials tailored to the needs of women living with and beyond ovarian cancer. Our advocates have emphasized a key principle: return of value. This concept involves ensuring that participants—whether research subjects or advocates—receive meaningful, actionable information in formats that are accessible to them. Responding to this need, MOCOG is co-designing a suite of lay materials summarizing our study findings, including visual abstracts and short-form audio and video content. This multipronged approach acknowledges diverse preferences and literacy levels within the survivor community, maximizing reach and impact. Input from advocates has driven our development process, from topic selection through to format and distribution channels. Recognizing advocates as integral partners, we have implemented mechanisms for their direct input, such as the creation of advocacy-driven question lists and interactive breakfast round tables with our expert research team. These efforts have catalyzed meaningful dialogue and mutual learning, reinforcing the importance of recognizing advocates as knowledge holders and ensuring the research process is responsive to their priorities. Also, advocates on MOCOG participated in research discussions and papers and were then in a position to advocate for follow-on studies that might help improve survival for women with ovarian cancer. Looking forward, study design processes are increasingly incorporating early-stage feedback from participants and advocates to ensure co-design and return of value are central considerations. This not only fosters trust and engagement but also increases the relevance and uptake of research findings within the survivor community. One example is the patient registry under development by Ovarian Cancer Research Alliance, which is built on the principles of early and continuous community engagement. Our experiences underscore the importance of designing research with return of value in mind, informed by authentic collaboration with those most impacted. As the field evolves, integrating community perspectives through partnerships and emerging platforms will be critical to maximizing the significance and reach of ovarian cancer research. Citation Format: Celeste Leigh Pearce, Gillian Hanley, Anne Chase, Cindy McKinnon. Deurloo, Jean Richardson, Bronwyn Grout. Full circle: Return of value to ovarian cancer research participants, advocates, and survivors [abstract]. In: Proceedings of the AACR Special Conference in Cancer Research: Advances in Ovarian Cancer Research; 2025 Sep 19-21; Denver, CO. Philadelphia (PA): AACR; Cancer Res 2025;85(18_Suppl):Abstract nr IA002.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.045
metaresearch head score (Gemma)0.175
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.072
Threshold uncertainty score0.241

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0450.175
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0060.003
Scholarly communication0.0110.006
Open science0.0020.011
Research integrity0.0040.006
Insufficient payload (model declined to judge)0.0720.021

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.113
GPT teacher head0.533
Teacher spread0.420 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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