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Record W4414397095 · doi:10.1370/afm.240472

An Innovative Strategy for Collecting Family Health History: An Effectiveness-Implementation Trial in Primary Care Clinics

2025· article· en· W4414397095 on OpenAlexaffabout
June Carroll, Michelle Greiver, Sahana Kukan, Erin Bearss, Sakina Walji, Rahim Moineddin, Babak Aliarzadeh, Sumeet Kalia, Judith Allanson, Eva Grunfeld, Karuna Gupta, Ruth Heisey, Doug Kavanagh, Raymond H. Kim, Michelle Levy, Shawna Morrison, Maria Muraca, Donatus Mutasingwa, Mary Ann O’Brien, Joanne Permaul, Brenda J. Wilson

Bibliographic record

VenueThe Annals of Family Medicine · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsMemorial University of NewfoundlandWomen's College HospitalMarkham Stouffville HospitalChildren's Hospital of Eastern OntarioUniversity of ManitobaNorth York General HospitalSinai Health SystemUniversity Health NetworkUniversity of Toronto
Fundersnot available
KeywordsPrimary careIntervention (counseling)Primary health careHealth careFamily healthPublic health

Abstract

fetched live from OpenAlex

PURPOSE We aimed to evaluate an innovative strategy to collect family history (FH) and explore patients’ views of this strategy. METHODS We conducted a matched-pair effectiveness-implementation trial in family practices affiliated with the University of Toronto Practice-Based Research Network (UTOPIAN). The intervention group included family physicians (FPs) from randomly selected practices using electronic health records (EHRs) and an e-mailing platform, and randomly selected patients aged 30-69 years (4/FP/week) seen in clinic over a 6-month period. The matched control group included FPs (1:1) and patients (up to 5:1) from the UTOPIAN database. The intervention included patient and FP education, an e-mailed patient invitation to complete an FH questionnaire, automatic FH EHR upload, FP notification of completed FH questionnaire, and links to clinical support tools. Intervention patients were e-mailed a postvisit follow-up questionnaire. The assessed outcome was new documentation of FH in the EHR using mixed effects logistic regression and descriptive statistics for patient feedback. RESULTS Fifteen FPs and 576 patients were recruited from 3 multidisciplinary team practices to the intervention group, matched to 15 FPs and 2,203 patients in the control group. Within 30 days of visit, a new FH was documented in the EHR for 93/576 (16.1%) of intervention patients compared with 5/2,203 (0.2%) control patients (adjusted OR = 94.2; 95% CI, 36.8-240.8). New cancer FH documentation was greater in the intervention group compared with the control group (7.8% vs 0.1%; P < .01). Of patients who reported discussing FH (n = 296), 24.5% reported screening test recommended, 7.5% referral to a nongenetics specialist, and 2.4% referral to a genetics specialist. Most patients (60.5%) found this FH strategy helpful. CONCLUSIONS This study showed improved collection/documentation of FH. Contributors to success of the intervention included being patient completed and seamless EHR integration with a reminder. This FH strategy needs tailoring to different contexts.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.023
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.124

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0230.023
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0010.001
Science and technology studies0.0020.003
Scholarly communication0.0020.003
Open science0.0020.002
Research integrity0.0040.002
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.258
GPT teacher head0.512
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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