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Record W4414441107 · doi:10.1016/j.euf.2025.09.001

Managing Genital Herpes: A Mini-review for Urologists from the European Association of Urology Guidelines Panel for Urological Infections

2025· review· en· W4414441107 on OpenAlexaff
Guglielmo Mantica, Jennifer Kranz, Tommaso Cai, Suzanne E. Geerlings, Béla Köves, Sören Schubert, Adrian Pilatz, José Medina‐Polo, Laila Schneidewind, Rajan Veeratterapillay, Florian Wagenlehner, Wout Devlies, Kathrin Bausch, Lorenz Leitner, Fabian P. Stangl, Hala Ali, Gernot Bonkat

Bibliographic record

VenueEuropean Urology Focus · 2025
Typereview
Languageen
FieldMedicine
TopicHerpesvirus Infections and Treatments
Canadian institutionsInstitute of Infection and Immunity
Fundersnot available
KeywordsDiseaseAsymptomaticSex organPsychosocialHerpes simplex virusSexually transmitted diseaseUrologic disease

Abstract

fetched live from OpenAlex

Genital herpes (GH) is a prevalent, lifelong, sexually transmitted infection caused by herpes simplex virus types 1 and 2. Although traditionally managed by dermatologists and infectious disease specialists, GH is increasingly relevant to urologists owing to its clinical complexity and psychosocial impact. This mini-review by the European Association of Urology Guidelines Panel for Urological Infections summarizes updated evidence on GH epidemiology, diagnosis, treatment, and prevention strategies. Diagnosis remains challenging because of atypical presentations; polymerase chain reaction is the preferred diagnostic test. Management mainly relies on nucleoside analogs, with new therapies under investigation. Suppressive treatment reduces recurrences and transmission. Routine screening of asymptomatic individuals is not recommended. Effective counseling and partner notification are critical components of care. PATIENT SUMMARY: Patients with genital herpes should receive clear information on the nature of the infection, the diagnostic process, and treatment options and preventive strategies. Urologists must play a key role in managing symptoms, reducing the risk of transmission, and supporting patients through education and counseling.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.008
Threshold uncertainty score0.027

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.002
Science and technology studies0.0000.000
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0080.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.095
GPT teacher head0.371
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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