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Record W4414475390 · doi:10.1016/j.jscai.2025.103937

Virtual Cath Lab: Versatile Open-Source Simulator for Education and Procedural Planning in Congenital Heart Interventions

2025· article· en· W4414475390 on OpenAlexaff
Yuval Barak‐Corren, Matthew Daemer, Mudit Gupta, Kyle Sunderland, András Lassó, Analise Sulentic, Trevor R. Williams, Silvani Amin, Alana Cianciulli, Michael L. O’Byrne, Matthew A. Jolley

Bibliographic record

VenueJournal of the Society for Cardiovascular Angiography & Interventions · 2025
Typearticle
Languageen
FieldEngineering
TopicAnatomy and Medical Technology
Canadian institutionsQueen's University
FundersNational Institutes of HealthChildren's Hospital of Philadelphia
KeywordsFluoroscopyVisualizationBiplaneCardiac catheterizationVirtual patientVascular accessPsychological interventionComputed tomography

Abstract

fetched live from OpenAlex

Background: Transcatheter cardiac interventions in congenital heart disease require a precise understanding of 3-dimensional (3D) anatomical structures represented through projectional angiograms. However, intraprocedural optimization of angiograms is limited by the need to reduce exposure to radiation and nephrogenic contrast. Preprocedural optimization using 3D images has the potential to improve patient outcomes and trainee education. We sought to simulate fluoroscopic projections from 3D computed tomography images within an integrated procedural planning framework with the goal of informing training and the planning of complex interventions. Methods: We developed the Virtual Cath Lab simulator in SlicerHeart to generate fluoroscopic projections from cross-sectional 3D images contextualized in a realistic biplane C-arm model. Segmented images were used to simulate angiograms. Simulated projections were compared to actual angiograms obtained in the catheterization laboratory to assess realism and accuracy. Results: The Virtual Cath Lab allowed realistic movement of a C-arm model in synchrony with the generation of realistic fluoroscopic projections. Seventeen subjects were modeled (10 ductus arteriosus stents, 4 transcatheter pulmonary valve replacement, 1 tetralogy of Fallot with major aortopulmonary collateral arteries, 1 aortopulmonary fistula, and 1 reverse Potts shunt). The simulator successfully generated fluoroscopic projections of each subject, rapidly producing clear and anatomically accurate images, suitable for procedural planning in all cases. Conclusions: We report the development and application of an open-source, freely available, biplane fluoroscopy simulator based on computed tomography images. Integrated visualization of complex vascular anatomy prior to catheterization may facilitate optimization of fluoroscopic angles and procedural decision-making while also supporting education. Further studies are needed to demonstrate the clinical and educational benefits.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (broad)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.814
Threshold uncertainty score0.966

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.043
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.293
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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