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Record W4414491246 · doi:10.1098/rsbl.2025.0316

Rethinking thecodonty: the influence of two centuries of comparative dental anatomy on our understanding of tooth evolution

2025· article· en· W4414491246 on OpenAlexafffund
Gabriel Mestriner, Gregory F. Funston, Júlio C. A. Marsola, Sterling J. Nesbitt, Max C. Langer, David C. Evans, Aaron R. H. LeBlanc

Bibliographic record

VenueBiology Letters · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
Topicdental development and anomalies
Canadian institutionsRoyal Ontario MuseumUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of CanadaUniversity of TorontoFundação de Amparo à Pesquisa do Estado de São PauloNational Geographic SocietyDivision of Earth SciencesNational Science Foundation
KeywordsAmnioteHeterochronyCementumPeriodontiumDental alveolusAnkylosisConfusionDental cementum

Abstract

fetched live from OpenAlex

'Thecodont' refers to teeth implanted in sockets within the jaw, a condition traditionally associated with living mammals and crocodylians, which also coincidentally have teeth attached by ligaments to the socket walls (gomphosis). For over a century, the bony periodontium of many other amniotes has been described as a single tissue, 'bone of attachment', causing confusion over dental tissue homology. The conventional definitions of 'thecodonty' exclude species with fused teeth ('ankylothecodonts'), implying a fundamental difference between mammals, crocodylians and most other vertebrates. However, the stereotypically 'thecodont' attachment tissues have been discovered in representatives of all major amniote clades, showing that gomphosis and ankylosis likely stem from heterochronic changes in the timing and extent of cementum and alveolar bone mineralization. This challenges (i) previous hypotheses regarding the evolution of the amniote periodontium, (ii) the 'bone of attachment' paradigm, and (iii) the significance of 'thecodonty'. We suggest a new nomenclatural approach that incorporates recent histological and evolutionary research and divides thecodonty into anatomical categories to clarify their origin and evolution. We propose the terms anisothecodont and isothecodont to denote, respectively, asymmetric and symmetric implantation of teeth in their sockets. Regardless of the geometry of the connection, we propose using ankylosis and gomphosis to denote the mode of tooth attachment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.070
Threshold uncertainty score0.228

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.295
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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