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Record W4414507637 · doi:10.3138/ptc-2024-0136

Prospective Classification of Functional Dependence: Insights from Machine Learning and the Canadian Longitudinal Study on Aging

2025· article· en· W4414507637 on OpenAlexaffvenueabout
Zack van Allen, Matthieu P. Boisgontier

Bibliographic record

VenuePhysiotherapy Canada · 2025
Typearticle
Languageen
FieldMedicine
TopicFrailty in Older Adults
Canadian institutionsInstitut du Savoir MontfortCARE CanadaBruyèreMontfort HospitalUniversity of Ottawa
Fundersnot available
KeywordsLogistic regressionBaseline (sea)Longitudinal studyActivities of daily livingPsychological interventionSet (abstract data type)Test (biology)Regression analysis

Abstract

fetched live from OpenAlex

Purpose: Functional dependence affects well-being and life expectancy. We identified baseline variables that best predict future limitations in basic and instrumental activities of daily living. Method: Using a filtering approach, we selected the best predictors from 4,248 candidate predictors for 39,927 Canadian Longitudinal Study on Aging participants aged 44–88 years and compared machine learning models trained on baseline data (2010–2015) on their ability to classify functional status (independent vs. dependent people) at follow-up (2018–2021) in a training set ( n = 31,941). We then tested the best model in a separate test set ( n = 7,986). Results: Eighteen variables best predicted functional status at follow-up. Logistic regression performed best, achieving 81.9% balanced accuracy in the test set. Protective factors included no baseline limitations, stronger grip, absence of pain or chronic conditions, female sex, having a driver’s license, and good memory. Risk factors included older age, psychological distress, slow walking, retirement, chronic conditions, and physical inactivity. Conclusion: Functional status can be predicted up to 6 years in advance using health, demographic, cognitive, and physical activity variables. Early identification may enable timely interventions to delay functional decline.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.018
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.054
Threshold uncertainty score0.110

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.018
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.003
Science and technology studies0.0020.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.299
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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