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Record W4414535735 · doi:10.1177/01622439251378192

From Neighborhoods to Molecules: The Selective Appropriation of Sociology in Social Epigenetics

2025· article· en· W4414535735 on OpenAlexaff
Julien Larrègue, Séverine Louvel

Bibliographic record

VenueScience Technology & Human Values · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRace, Genetics, and Society
Canadian institutionsUniversité Laval
FundersInstitut Universitaire de France
KeywordsAppropriationSocial researchQualitative researchSocial epidemiologySociology of health and illnessEpigeneticsSocial complexitySocial theory

Abstract

fetched live from OpenAlex

Social epigenetics is presented as a promising interdisciplinary avenue between the natural and social sciences to explore the links between neighborhood environments, epigenetic modifications and health outcomes. Sociological concepts and methods are mobilized, sometimes through direct collaboration between epidemiologists and sociologists, to grasp the embodiment of social inequalities. Drawing on an in-depth qualitative analysis of three epidemiological cohort studies in the United States, we offer a processual approach to the use of Chicago-style ecological research on disorganization in social epigenetic studies. We argue that a selective appropriation of sociological research operates at two different levels of study design: that of the overall cohort study in which social epigenetics research is conducted and data are obtained, and that of the social epigenetics studies. This selective appropriation represents one of the most successful attempts in social epigenetics to complexify concepts and methods for analyzing health outcomes as a product of social situations. We show that for the epidemiologists and sociologists working in this interdisciplinary space, the move to greater complexity means observing the social organization of neighborhoods from a rather narrow window of observation, but one that presumably allows them to produce robust statistical evidence for the biological embodiment of social conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.022
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.995
Threshold uncertainty score0.117

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0220.023
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0040.002
Science and technology studies0.0050.088
Scholarly communication0.0100.012
Open science0.0010.011
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.305
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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