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Record W4414542590 · doi:10.26443/mjgh.v14i1.1664

Genetic Manipulation of Homeobox Genes in Female Anopheles Mosquitoes to Curb Malaria: A Medical Entomology Perspective

2025· article· en· W4414542590 on OpenAlexaff
Nina Anastasia Zevgolis

Bibliographic record

VenueMcGill Journal of Global Health · 2025
Typearticle
Languageen
FieldMedicine
TopicMosquito-borne diseases and control
Canadian institutionsMcGill UniversityEnvironment and Climate Change Canada
Fundersnot available
KeywordsMalariaEntomologyAnophelesPerspective (graphical)DiseasePublic healthGene drivePlasmodium yoelii

Abstract

fetched live from OpenAlex

At 249 million cases and 608,000 fatalities reported in 2022, malaria remains a major global health challenge, disproportionately affecting Sub-Saharan Africa, and accounting for 95% of malaria-related deaths. The disease is caused by Plasmodium parasites and is transmitted by Anopheles mosquitoes, exacerbated by damp climatic conditions, political instability, and inadequate healthcare infrastructure.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.242
Threshold uncertainty score0.480

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.368
Teacher spread0.352 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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